[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Solid lipid nanoparticles for hydrophilic drugs

Y Mirchandani, VB Patravale, S Brijesh - Journal of Controlled Release, 2021 - Elsevier
Hydrophilic drugs are proficient therapeutic agents however, delivery of these drugs is a
difficult task. Hence, developing an efficient drug delivery system may require a …

[HTML][HTML] Gene therapy in cancer treatment: why go nano?

C Roma-Rodrigues, L Rivas-García, PV Baptista… - Pharmaceutics, 2020 - mdpi.com
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections

S Subramaniam, P Joyce, N Thomas… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …

Design, characterization and in vivo performance of solid lipid nanoparticles (SLNs)-loaded mucoadhesive buccal tablets for efficient delivery of Lornoxicam in …

MB Zewail, GF Asaad, SM Swellam… - International Journal of …, 2022 - Elsevier
Lornoxicam (LRX) is a potent nonsteroidal anti-inflammatory drug (NSAID) used extensively
to manage pain and inflammatory conditions. However, the drug possesses poor aqueous …

Perspectives and prospective on solid lipid nanoparticles as drug delivery systems

OA Madkhali - Molecules, 2022 - mdpi.com
Combating multiple drug resistance necessitates the delivery of drug molecules at the
cellular level. Novel drug delivery formulations have made it possible to improve the …

Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: A review

AV Samrot, TC Sean, T Kudaiyappan… - International Journal of …, 2020 - Elsevier
Chitosan, collagen, gelatin, polylactic acid and polyhydroxyalkanoates are notable
examples of biopolymers, which are essentially bio-derived polymers produced by living …

The current therapeutical strategies in human brucellosis

M Bosilkovski, F Keramat, J Arapović - Infection, 2021 - Springer
Prompt and adequate treatment of human brucellosis continues to be the most important
strategy in its management, as eradication of animal brucellosis is not possible so far, and …

[HTML][HTML] Nano drug delivery in intracellular bacterial infection treatments

SM Hosseini, M Taheri, F Nouri, A Farmani… - Biomedicine & …, 2022 - Elsevier
The present work aimed to review the potential mechanisms used by macrophages to kill
intracellular bacteria, their entrance to the cell, and mechanisms of escape of cellular …

Incorporation of antibiotics into solid lipid nanoparticles: a promising approach to reduce antibiotic resistance emergence

L Arana, L Gallego, I Alkorta - Nanomaterials, 2021 - mdpi.com
Antimicrobial resistance is one of the biggest threats to global health as current antibiotics
are becoming useless against resistant infectious pathogens. Consequently, new …