[HTML][HTML] Cat-Map: putting cataract on the map
A Shiels, TM Bennett, JF Hejtmancik - Molecular vision, 2010 - ncbi.nlm.nih.gov
Lens opacities, or cataract (s), may be inherited as a classic Mendelian disorder usually with
early-onset or, more commonly, acquired with age as a multi-factorial or complex trait. Many …
early-onset or, more commonly, acquired with age as a multi-factorial or complex trait. Many …
The role of corneal crystallins in the cellular defense mechanisms against oxidative stress
N Lassen, WJ Black, T Estey, V Vasiliou - Seminars in cell & developmental …, 2008 - Elsevier
The refracton hypothesis describes the lens and cornea together as a functional unit that
provides the proper ocular transparent and refractive properties for the basis of normal …
provides the proper ocular transparent and refractive properties for the basis of normal …
[HTML][HTML] Genetic polymorphisms of superoxide dismutases, catalase, and glutathione peroxidase in age-related cataract
Y Zhang, L Zhang, DL Sun, ZS Li, L Wang, P Liu - Molecular vision, 2011 - ncbi.nlm.nih.gov
Purpose The antioxidant enzymes pathway is considered the most important pathway
involved in the repair of reactive oxygen species (ROS)–induced damage. Therefore, we …
involved in the repair of reactive oxygen species (ROS)–induced damage. Therefore, we …
Gene–environment interactions in ocular diseases
SC Sacca, C Bolognesi, A Battistella, A Bagnis… - Mutation Research …, 2009 - Elsevier
Degenerative ocular diseases are widespread in the population and represent a major
cause of reversible and irreversible blindness. Scientific evidences have been accumulating …
cause of reversible and irreversible blindness. Scientific evidences have been accumulating …
Role of carcinogenesis related mechanisms in cataractogenesis and its implications for ionizing radiation cataractogenesis
N Hamada, Y Fujimichi - Cancer Letters, 2015 - Elsevier
Ionizing radiation is a proven human carcinogen and cataractogen. The crystalline lens of
the eye is among the most radiosensitive tissues in the body. A clouding of the normally …
the eye is among the most radiosensitive tissues in the body. A clouding of the normally …
Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk
C Dalke, F Neff, SK Bains, S Bright, D Lord… - Radiation and …, 2018 - Springer
Because of the increasing application of ionizing radiation in medicine, quantitative data on
effects of low-dose radiation are needed to optimize radiation protection, particularly with …
effects of low-dose radiation are needed to optimize radiation protection, particularly with …
Oxidative Stress, Helicobacter pylori, and OGG1 Ser326Cys, XPC Lys939Gln, and XPD Lys751Gln Polymorphisms in a Turkish Population with Colorectal …
The contribution of polymorphisms of DNA repair genes OGG1 Ser326Cys, XPC Lys939Gln,
and XPD Lys751Gln in developing colorectal carcinoma is controversial. Whether the group …
and XPD Lys751Gln in developing colorectal carcinoma is controversial. Whether the group …
[HTML][HTML] Polymorphisms in two DNA repair genes (XPD and XRCC1)–association with age related cataracts
G Padma, M Mamata, KRK Reddy, T Padma - Molecular vision, 2011 - ncbi.nlm.nih.gov
Purpose Age related cataract is the leading cause of blindness in the world today. The
association between DNA damage to the lens epithelium and the development of lens …
association between DNA damage to the lens epithelium and the development of lens …
Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract
Y Zhang, L Zhang, Z Song, DL Sun, HR Liu, SB Fu… - Ophthalmology, 2012 - Elsevier
PURPOSE: To analyze the association of the polymorphisms in 8-oxoguanine glycosylase-1
(OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) …
(OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) …
New Mutation in the Mouse Xpd/Ercc2 Gene Leads to Recessive Cataracts
S Kunze, C Dalke, H Fuchs, M Klaften, U Rössler… - PLoS …, 2015 - journals.plos.org
Cataracts are the major eye disorder and have been associated mainly with mutations in
lens-specific genes, but cataracts are also frequently associated with complex syndromes. In …
lens-specific genes, but cataracts are also frequently associated with complex syndromes. In …