Fungal strategies to evade the host immune recognition

MJ Hernández-Chávez, LA Pérez-García… - Journal of Fungi, 2017 - mdpi.com
The recognition of fungal cells by the host immune system is key during the establishment of
a protective anti-fungal response. Even though the immune system has evolved a vast …

Ficolins and the recognition of pathogenic microorganisms: an overview of the innate immune response and contribution of single nucleotide polymorphisms

S Bidula, DW Sexton, S Schelenz - Journal of immunology …, 2019 - Wiley Online Library
Ficolins are innate pattern recognition receptors (PRR) and play integral roles within the
innate immune response to numerous pathogens throughout the circulation, as well as …

Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

A Doni, R Parente, I Laface, E Magrini, C Cunha… - Nature …, 2021 - nature.com
Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component
of the humoral arm of innate immunity involved in resistance to bacterial infection and …

Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins

R Shende, SSW Wong, S Rapole, R Beau… - Journal of Biological …, 2018 - ASBMB
Innate immunity in animals including humans encompasses the complement system, which
is considered an important host defense mechanism against Aspergillus fumigatus, one of …

Interplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus

S Dellière, C Chauvin, SSW Wong, M Gressler… - Nature …, 2024 - nature.com
Abstract Pentraxin 3 (PTX3), a long pentraxin and a humoral pattern recognition molecule
(PRM), has been demonstrated to be protective against Aspergillus fumigatus, an airborne …

Cyclodextrin reduces cholesterol crystal–induced inflammation by modulating complement activation

SS Bakke, MH Aune, N Niyonzima, K Pilely… - The Journal of …, 2017 - journals.aai.org
Cholesterol crystals (CC) are abundant in atherosclerotic plaques and promote inflammatory
responses via the complement system and inflammasome activation. Cyclic oligosaccharide …

The complement system in Aspergillus fumigatus infections and its crosstalk with pentraxins

R Parente, A Doni, B Bottazzi, C Garlanda… - FEBS …, 2020 - Wiley Online Library
Aspergillosis is a life‐threatening infection mostly affecting immunocompromised individuals
and primarily caused by the saprophytic fungus Aspergillus fumigatus. At the host–pathogen …

Complementary Roles of Short and Long Pentraxins in the Complement-Mediated Immune Response to Aspergillus fumigatus Infections

R Parente, V Possetti, M Erreni, F D'Autilia… - Frontiers in …, 2021 - frontiersin.org
The ubiquitous mold Aspergillus fumigatus is the major etiologic agent of invasive
aspergillosis, a life-threatening infection amongst immune compromised individuals. An …

[HTML][HTML] Synergistic immunoreaction of acupuncture-like dissolving microneedles containing thymopentin at acupoints in immune-suppressed rats

Q Zhang, C Xu, S Lin, H Zhou, G Yao, H Liu… - … pharmaceutica sinica B, 2018 - Elsevier
Dissolving microneedles carried drug molecules can effectively penetrate the stratum
corneum of skin to improve the transdermal drug delivery. The traditional Chinese medicine …

An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation

YJ Ma, BL Lee, P Garred - Experimental & molecular medicine, 2017 - nature.com
The complement system is an innate immune defense machinery comprising components
that deploy rapid immune responses and provide efficient protection against foreign …