[HTML][HTML] Counterdiffusion methods applied to protein crystallization

F Otálora, JA Gavira, JD Ng, JM García-Ruiz - Progress in biophysics and …, 2009 - Elsevier
Accumulated experience during the last years on counterdiffusion crystallization methods
shows that they are a convenient and generally applicable way of optimizing solution crystal …

[PDF][PDF] Practical macromolecular cryocrystallography

JW Pflugrath - Acta Crystallographica Section F: Structural Biology …, 2015 - journals.iucr.org
Cryocrystallography is an indispensable technique that is routinely used for single-crystal X-
ray diffraction data collection at temperatures near 100 K, where radiation damage is …

A droplet‐based, composite PDMS/glass capillary microfluidic system for evaluating protein crystallization conditions by microbatch and vapor‐diffusion methods with …

B Zheng, JD Tice, LS Roach… - Angewandte chemie …, 2004 - Wiley Online Library
This paper reports a composite microfluidic system for performing protein crystallization trials
in nanoliter aqueous droplets inside capillaries suitable for X-ray diffraction and the …

Integrated chip carriers with thermocycler interfaces and methods of using the same

G Facer, R Grossman, M Unger, P Lam… - US Patent …, 2010 - Google Patents
(60) Provisional application No. 60/558.316, filed on Mar. mal control source. Reagents for
carrying out a desired reac 30, 2004, provisional application No. 60/557,715, tion are …

Integrated chip carriers with thermocycler interfaces and methods of using the same

G Facer, R Grossman, M Unger, P Lam… - US Patent …, 2011 - Google Patents
Methods and systems are provided for conducting a reaction at a selected temperature or
range of temperatures over time. An array device is provided. The array device contains …

Protein crystallization by capillary counterdiffusion for applied crystallographic structure determination

JD Ng, JA Gavira, JM Garcı́a-Ruı́z - Journal of structural biology, 2003 - Elsevier
Counterdiffusion crystallization in capillary is a very simple, cost-effective, and practical
procedure for obtaining protein crystals suitable for X-ray data analysis. Its principles have …

Microfluidic chips for the crystallization of biomacromolecules by counter-diffusion and on-chip crystal X-ray analysis

K Dhouib, CK Malek, W Pfleging, B Gauthier-Manuel… - Lab on a Chip, 2009 - pubs.rsc.org
Microfluidic devices were designed to perform on micromoles of biological macromolecules
and viruses the search and the optimization of crystallization conditions by counter-diffusion …

Counterdiffusion methods for macromolecular crystallization

JM García-Ruiz - Methods in Enzymology, 2003 - Elsevier
Publisher Summary This chapter deals with the counterdiffusion methods for
macromolecular crystallization. The chapter gives a basic introduction to the use of the …

Granada Crystallisation Box: a new device for protein crystallisation by counter-diffusion techniques

JM Garcia-Ruiz, LA Gonzalez-Ramirez… - … Section D: Biological …, 2002 - journals.iucr.org
Granada Crystallisation Box (GCB) is a new crystallisation device designed to perform
counter-diffusion experiments. Here we describe the device and its use for protein …

Microfluidic reaction apparatus for high throughput screening

RC Jones, P Wyatt, A Daridon, J Wang, A May… - US Patent …, 2010 - Google Patents
US7815868B1 - Microfluidic reaction apparatus for high throughput screening - Google Patents
US7815868B1 - Microfluidic reaction apparatus for high throughput screening - Google Patents …