Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma

YT Chan, C Zhang, J Wu, P Lu, L Xu, H Yuan, Y Feng… - Molecular Cancer, 2024 - Springer
Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

A Colli, T Nadarevic, D Miletic, V Giljaca… - Cochrane Database …, 2021 - cochranelibrary.com
Background Hepatocellular carcinoma (HCC) occurs mostly in people with chronic liver
disease and ranks sixth in terms of global instances of cancer, and fourth in terms of cancer …

[HTML][HTML] Integrative bioinformatics and experimental analysis revealed TEAD as novel prognostic target for hepatocellular carcinoma and its roles in ferroptosis …

X Ren, X Wang, Y Yan, X Chen, Y Cai, Q Liang… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Objective: Transcriptional enhanced associate domain (TEAD) family consists of four
members TEAD1/2/3/4 that regulate cell growth, stem cell functions and organ development …

基于血液DNA 甲基化在肝癌诊断中的研究进展

李芳芳, 陶紫薇, 沈永利, 翁亚丽 - 实用临床医药杂志, 2021 - jcmp.yzu.edu.cn
肝癌是世界范围内致死率最高的癌症之一, 早期诊断率低, 通常在发现肝癌时患者已经处于晚期.
早期诊断是降低肝癌患者死亡率的重要手段, 但目前尚无诊断肝癌的可靠血液学分子标志物 …

早期肝癌无创诊断之匙———循环游离DNA 联合型液体活检.

叶婷丹, 雷学忠 - Journal of Clinical Hepatology/Linchuang …, 2022 - search.ebscohost.com
循环游离DnA (cfDnA) 被认为是诊断早期肝癌极具研究前景的液体活检切入点.
但不少研究证实单独使用cfDnA 作为检测指标其诊断效能缺乏稳定性, 尤其是单纯定量分析并 …

Circulating cell-free DNA-combined liquid biopsy: The key to noninvasive diagnosis of early-stage liver cancer

YE Tingdan, LEI Xuezhong - 临床肝胆病杂志, 2022 - lcgdbzz.org
Circulating cell-free DNA (cfDNA) is considered a promising entry point of liquid biopsy for
the diagnosis of early-stage liver cancer; however, many studies have confirmed that the …