Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer
Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
Biodistribution of extracellular vesicles following administration into animals: A systematic review
M Kang, V Jordan, C Blenkiron… - Journal of extracellular …, 2021 - Wiley Online Library
In recent years, attention has turned to examining the biodistribution of EVs in recipient
animals to bridge between knowledge of EV function in vitro and in vivo. We undertook a …
animals to bridge between knowledge of EV function in vitro and in vivo. We undertook a …
[HTML][HTML] The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy
Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …
A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication
Extracellular vesicles (EVs) are small, membrane-bound structures that are released from
cells into the surrounding environment. These structures can be categorized as exosomes …
cells into the surrounding environment. These structures can be categorized as exosomes …
Engineered extracellular vesicles for cancer therapy
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics
A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
Extracellular vesicles versus synthetic nanoparticles for drug delivery
Cell-released biological nanoparticles, that is, extracellular vesicles (EVs), are emerging
drug carriers with high complexity. EV-based drug delivery exploits intrinsic mechanisms for …
drug carriers with high complexity. EV-based drug delivery exploits intrinsic mechanisms for …
Extracellular vesicles: a rising star for therapeutics and drug delivery
S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
Entry and exit of extracellular vesicles to and from the blood circulation
Extracellular vesicles (EVs) are biological nanoparticles that promote intercellular
communication by delivering bioactive cargo over short and long distances. Short-distance …
communication by delivering bioactive cargo over short and long distances. Short-distance …