Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status

CWJ van der Weijden, E Biondetti, IW Gutmann… - Brain, 2023 - academic.oup.com
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Spinal cord fMRI: A new window into the central nervous system

N Kinany, E Pirondini, S Micera… - The …, 2023 - journals.sagepub.com
With the brain, the spinal cord forms the central nervous system. Initially considered a
passive relay between the brain and the periphery, the spinal cord is now recognized as …

[HTML][HTML] Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

J Cohen-Adad, E Alonso-Ortiz, M Abramovic, C Arneitz… - Scientific Data, 2021 - nature.com
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI
protocol that provides valuable metrics for assessing spinal cord macrostructural and …

[HTML][HTML] Utility of MRI in quantifying tissue injury in cervical spondylotic myelopathy

AF Khan, G Haynes, E Mohammadi… - Journal of Clinical …, 2023 - mdpi.com
Cervical spondylotic myelopathy (CSM) is a progressive disease that worsens over time if
untreated. However, the rate of progression can vary among individuals and may be …

[HTML][HTML] Towards reliable spinal cord fMRI: Assessment of common imaging protocols

N Kinany, E Pirondini, L Mattera, R Martuzzi, S Micera… - NeuroImage, 2022 - Elsevier
Functional magnetic resonance imaging (fMRI) has revolutionized the investigation of brain
function. Similar approaches can be translated to probe spinal mechanisms. However …

[HTML][HTML] Reliability of resting-state functional connectivity in the human spinal cord: assessing the impact of distinct noise sources

M Kaptan, U Horn, SJ Vannesjo, T Mildner, N Weiskopf… - Neuroimage, 2023 - Elsevier
The investigation of spontaneous fluctuations of the blood-oxygen-level-dependent (BOLD)
signal has recently been extended from the brain to the spinal cord, where it has stimulated …

Vendor‐neutral sequences and fully transparent workflows improve inter‐vendor reproducibility of quantitative MRI

A Karakuzu, L Biswas, J Cohen‐Adad… - Magnetic Resonance …, 2022 - Wiley Online Library
Purpose We developed an end‐to‐end workflow that starts with a vendor‐neutral acquisition
and tested the hypothesis that vendor‐neutral sequences decrease inter‐vendor variability …

A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations

L Liang, A Damiani, M Del Brocco… - The Journal of …, 2023 - Wiley Online Library
Seventy years ago, Hodgkin and Huxley published the first mathematical model to describe
action potential generation, laying the foundation for modern computational neuroscience …

[HTML][HTML] Peripheral white blood cell responses as emerging biomarkers for patient stratification and prognosis in acute spinal cord injury

T Jogia, MA Kopp, JM Schwab… - Current Opinion in …, 2021 - journals.lww.com
Peripheral white blood cell responses as emerging biomarkers... : Current Opinion in
Neurology Peripheral white blood cell responses as emerging biomarkers for patient …

[HTML][HTML] Reliability of multi-parameter mapping (MPM) in the cervical cord: A multi-center multi-vendor quantitative MRI study

M Seif, T Leutritz, S Schading, T Emmengger, A Curt… - Neuroimage, 2022 - Elsevier
MRI based multicenter studies which target neurological pathologies affecting the spinal
cord and brain–including spinal cord injury (SCI)–require standardized acquisition protocols …