Physical constraints and forces involved in phagocytosis

V Jaumouillé, CM Waterman - Frontiers in immunology, 2020 - frontiersin.org
Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …

Sorting nexins provide diversity for retromer-dependent trafficking events

PJ Cullen, HC Korswagen - Nature cell biology, 2012 - nature.com
Sorting nexins are a large family of evolutionarily conserved phosphoinositide-binding
proteins that have fundamental roles in orchestrating cargo sorting through the membranous …

Mechanics of dynamin-mediated membrane fission

S Morlot, A Roux - Annual review of biophysics, 2013 - annualreviews.org
In eukaryotic cells, membrane compartments are split into two by membrane fission. This
ensures discontinuity of membrane containers and thus proper compartmentalization. The …

An endophilin–dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling

A Sundborger, C Soderblom… - Journal of cell …, 2011 - journals.biologists.com
Clathrin-mediated vesicle recycling in synapses is maintained by a unique set of endocytic
proteins and interactions. We show that endophilin localizes in the vesicle pool at rest and in …

Membrane constriction and thinning by sequential ESCRT-III polymerization

HC Nguyen, N Talledge, J McCullough, A Sharma… - Biophysical …, 2020 - cell.com
The Endosomal Sorting Complexes Required for Transport (ESCRTs) mediate diverse
membrane remodeling events. These activities typically require ESCRT-III proteins to …

Endocytic accessory factors and regulation of clathrin-mediated endocytosis

CJ Merrifield, M Kaksonen - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
Up to 60 different proteins are recruited to the site of clathrin-mediated endocytosis in an
ordered sequence. These accessory proteins have roles during all the different stages of …

Mechanics of surface area regulation in cells examined with confined lipid membranes

M Staykova, DP Holmes, C Read… - Proceedings of the …, 2011 - National Acad Sciences
Cells are wrapped in inelastic membranes, yet they can sustain large mechanical strains by
regulating their area. The area regulation in cells is achieved either by membrane folding or …

Targeting bacterial cardiolipin enriched microdomains: an antimicrobial strategy used by amphiphilic aminoglycoside antibiotics

M El Khoury, J Swain, G Sautrey, L Zimmermann… - Scientific reports, 2017 - nature.com
Some bacterial proteins involved in cell division and oxidative phosphorylation are tightly
bound to cardiolipin. Cardiolipin is a non-bilayer anionic phospholipid found in bacterial …

Hydrophobicity‐Adaptive Polymers Trigger Fission of Tumor‐Cell‐Derived Microparticles for Enhanced Anticancer Drug Delivery

H Liu, S Xu, T Yong, Z Wei, N Bie, X Zhang… - Advanced …, 2023 - Wiley Online Library
Tumor‐cell‐derived microparticles (MPs) can function as anticancer drug‐delivery carriers.
However, short blood circulation time, large‐size‐induced insufficient tumor accumulation …

Mendelian disorders of membrane trafficking

MA De Matteis, A Luini - New England Journal of Medicine, 2011 - Mass Medical Soc
Mendelian Disorders of Membrane Trafficking | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …