Porous materials are ubiquitous and exhibit properties suitable for depositing therapeutic
compounds. Drug loading in porous materials can protect the drug, control its release rate …

Porous silica-based drug delivery systems have shown considerable promise for improving
the oral delivery of poorly water-soluble drugs. More specifically, micro-and meso-porous …

Amorphous pharmaceutical solids (APS) are single-or multi-component systems in which
drugs exist in high-energy states with long-range disordered molecular packing. APSs have …

Amorphization is one of the most effective pharmaceutical approaches to enhance the
dissolution and oral bioavailability of poorly water-soluble drugs. In recent years, amorphous …

Many advancements are happening in drug delivery to develop an excellent nanocarrier to
deliver drugs to target sites bypassing clinical barriers, thereby improving cellular uptake …

Ordered mesoporous silica materials have shown great potential as oral drug delivery
systems for poorly soluble drugs. However, the ability of these delivery systems to generate …

Two different types of ordered mesoporous nanoparticles, namely MCM-41 and MCM-48,
with similar pore sizes but different pore connectivity, were loaded with aprepitant via a …

Drug-coformer systems, such as coamorphous and cocrystal, are gaining recognition as
highly effective strategies for enhancing the stability, solubility, and dissolution of drugs …

Loading poorly soluble active pharmaceutical ingredients (API) into mesoporous silica can
enable API stabilization in non-crystalline form, which leads to improved dissolution. This is …

Ordered mesoporous silica (OMS) materials have received significant attention in recent
years for use as effective supersaturating oral delivery systems for poorly water-soluble …