An overview of microRNAs

SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

[HTML][HTML] Sunitinib resistance in renal cell carcinoma: From molecular mechanisms to predictive biomarkers

J Jin, Y Xie, JS Zhang, JQ Wang, SJ Dai, W He… - Drug Resistance …, 2023 - Elsevier
Currently, renal cell carcinoma (RCC) is the most prevalent type of kidney cancer. Targeted
therapy has replaced radiation therapy and chemotherapy as the main treatment option for …

Isolation of exosomes from whole blood by integrating acoustics and microfluidics

M Wu, Y Ouyang, Z Wang, R Zhang… - Proceedings of the …, 2017 - National Acad Sciences
Exosomes are nanoscale extracellular vesicles that play an important role in many
biological processes, including intercellular communications, antigen presentation, and the …

Extracellular vesicles from red blood cells and their evolving roles in health, coagulopathy and therapy

K Thangaraju, SN Neerukonda, U Katneni… - International journal of …, 2020 - mdpi.com
Red blood cells (RBCs) release extracellular vesicles (EVs) including both endosome-
derived exosomes and plasma-membrane-derived microvesicles (MVs). RBC-derived EVs …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

MicroRNAs and their role on fish oxidative stress during xenobiotic environmental exposures

MA Burgos-Aceves, A Cohen, Y Smith… - … and Environmental safety, 2018 - Elsevier
There is a growing global concern about the health implications of xenobiotics, which have
harmful effects to both humans and wildlife. Among them, teleost fish are known as very …

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

S Cheloufi, CO Dos Santos, MMW Chong, GJ Hannon - Nature, 2010 - nature.com
The nucleolytic activity of animal Argonaute proteins is deeply conserved, despite its having
no obvious role in microRNA-directed gene regulation. In mice, Ago2 (also known as Eif2c2) …

Regulation of microRNA function in somatic stem cell proliferation and differentiation

A Shenoy, RH Blelloch - Nature reviews Molecular cell biology, 2014 - nature.com
Abstract microRNAs (miRNAs) are important modulators of development. Owing to their
ability to simultaneously silence hundreds of target genes, they have key roles in large-scale …

A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity

D Cifuentes, H Xue, DW Taylor, H Patnode, Y Mishima… - Science, 2010 - science.org
Dicer is a central enzyme in microRNA (miRNA) processing. We identified a Dicer-
independent miRNA biogenesis pathway that uses Argonaute2 (Ago2) slicer catalytic …

From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

SM Hattangadi, P Wong, L Zhang… - Blood, The Journal …, 2011 - ashpublications.org
This article reviews the regulation of production of RBCs at several levels. We focus on the
regulated expansion of burst-forming unit-erythroid erythroid progenitors by glucocorticoids …