Vitamin B 12 is an essential vitamin that is widely used in medical and food industries.
Vitamin B 12 biosynthesis is confined to few bacteria and archaea, and as such its …

This Feature Article highlights recent developments in the field of vitamin B12 derivatives for
medicinal applications. The following topics are emphasized:(1) the development of …

Mycobacterium tuberculosis is included among a select group of bacteria possessing the
capacity for de novo biosynthesis of vitamin B12, the largest and most complex natural …

RNA-based genetic regulation is exemplified by metabolite-binding riboswitches that
modulate gene expression through conformational changes. Crystal structures show that the …

Mg2+ has been shown to modulate the function of riboswitches by facilitating the ligand-
riboswitch interactions. The btuB riboswitch from Escherichia coli undergoes a …

Riboswitches are RNA-regulating elements that mostly rely on structural changes to
modulate gene expression at various levels. Recent studies have revealed that riboswitches …

Metabolite-dependent conformational switching in RNA riboswitches is now widely accepted
as a critical regulatory mechanism for gene expression in bacterial systems. More recently …

The unique feature of riboswitches is to control selected gene expression by specific
recognition of a cognate ligand. AdoCbl (adenosyl cobalamin, coenzyme B 12) riboswitches …

Sažetak Riboprekidači su nukleotidni sljedovi koji se nalaze u 5'netranslatiranim regijama
glasničke RNA i reguliraju gene uključene u biosintetske puteve esencijalnih metabolita …

Structured RNAs referred as riboswitches have been predicted to be present in the genome
sequence of Burkholderia pseudomallei strain K96243. Four of the riboswitches were …