How CD4+ lineage gene expression is initiated in differentiating thymocytes remains poorly
understood. Here, we show that the paralog transcription factors Zfp281 and Zfp148 control …

The MYC proto-oncogene (MYC) is one of the most frequently overexpressed genes in
breast cancer that drives cancer stem cell-like traits, resulting in aggressive disease …

Activating transcription factor 4 (Atf4), which is modulated by the protein kinase RNA-like ER
kinase (PERK), is a stress-induced transcription factor responsible for controlling the …

Erythropoiesis requires a combination of ubiquitous and tissue-specific transcription factors
(TFs). Here, through DNA affinity purification followed by mass spectrometry, we have …

RNA-based therapeutics are emerging as innovative options for cancer treatment, with
microRNAs being attractive targets for therapy development. We previously implicated …

Proper physiological function of mammalian airways requires the differentiation of basal
stem cells into secretory or multiciliated cells, among others. In addition, the self-renewal …

ZNF148 gene is a Krüppel‐type transcription factor that has transcriptional regulatory
function. Heterozygous variant in ZNF148 gene causes an intellectual disability syndrome …

:目的比较生物型短柄与标准柄在侧卧位直接前方入路(directanterior Page 1 侧卧位DAA下生物
型短柄与标准柄 THA治疗股骨头坏死的临床研究 郭达,彭侃,鲁超,许鹏 (西安交通大学附属红会 …

骨肉瘤(osteosarcoma, OS) 是最常见的原发性恶性骨肿瘤, 具有易发生转移, 预后差等特点,
多发于青少年[1]. 随着医疗科学发展, OS 的诊断和治疗方面取得了一些进展, 5 年生存率从20 …

PACT (encoded by the PRKRA gene) is a double-stranded RNA binding protein that has two
main functions in mammals: facilitation of antiviral defense mechanisms via the activation of …