The core mechanism of dry eye disease is inflammation
Y Wei, PA Asbell - Eye & contact lens, 2014 - journals.lww.com
Purpose: The purpose of this article is to review the evidence for the hypothesis that the core
mechanism of dry eye disease (DED) is inflammation, including evidence from recent basic …
mechanism of dry eye disease (DED) is inflammation, including evidence from recent basic …
Diagnosing the severity of dry eye: a clear and practical algorithm
C Baudouin, P Aragona, G Van Setten… - British Journal of …, 2014 - bjo.bmj.com
Dry eye disease (DED) is a distressing ocular condition. Due to its multifactorial nature,
clinical and biological signs of DED can be inconsistent and sometimes discordant with …
clinical and biological signs of DED can be inconsistent and sometimes discordant with …
Curcumin: a modulator of inflammatory signaling pathways in the immune system
KR Kahkhaie, A Mirhosseini, A Aliabadi… - …, 2019 - Springer
Curcumin is a natural compound derived from the spice, turmeric, that has been extensively
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …
[HTML][HTML] Dry eye disease and tear cytokine levels—a meta-analysis
M Roda, I Corazza, ML Bacchi Reggiani… - International journal of …, 2020 - mdpi.com
Background—It is recognized that inflammation is an underlying cause of dry eye disease
(DED), with cytokine release involved. We systematically reviewed literature with meta …
(DED), with cytokine release involved. We systematically reviewed literature with meta …
Clinical impact of inflammation in dry eye disease: proceedings of the ODISSEY group meeting
C Baudouin, M Irkeç, EM Messmer… - Acta …, 2018 - Wiley Online Library
Dry eye disease (DED) is a common, multifactorial ocular condition with major impact on
vision and quality of life. It is now well recognized that the pathophysiology of chronic DED …
vision and quality of life. It is now well recognized that the pathophysiology of chronic DED …
[HTML][HTML] NLRP3 inflammasome as a potential therapeutic target in dry eye disease
D Zhuang, SL Misra, OO Mugisho… - International Journal of …, 2023 - mdpi.com
Dry eye disease (DED) is a multifactorial ocular surface disorder arising from numerous
interrelated underlying pathologies that trigger a self-perpetuating cycle of instability …
interrelated underlying pathologies that trigger a self-perpetuating cycle of instability …
Dry eye exacerbation in patients exposed to desiccating stress under controlled environmental conditions
A López-Miguel, M Tesón, V Martín-Montañez… - American Journal of …, 2014 - Elsevier
Purpose To determine if controlled environmental conditions can induce acute
exacerbations of signs and symptoms in dry eye and asymptomatic subjects. Design …
exacerbations of signs and symptoms in dry eye and asymptomatic subjects. Design …
Role of NFAT5 in inflammatory disorders associated with osmotic stress
W Neuhofer - Current genomics, 2010 - ingentaconnect.com
Nuclear factor of activated T cells 5 (NFAT5) is the most recently described member of the
Rel family of transcription factors, including NF-κB and NFAT1-4, which play central roles in …
Rel family of transcription factors, including NF-κB and NFAT1-4, which play central roles in …
Rabbit models of ocular diseases: new relevance for classical approaches
EY Zernii, VE Baksheeva, EN Iomdina… - CNS & Neurological …, 2016 - ingentaconnect.com
Over 100 million individuals are affected by irreversible visual impairments and blindness
worldwide, while ocular diseases remain a challenging problem despite significant …
worldwide, while ocular diseases remain a challenging problem despite significant …
[HTML][HTML] TRPV1 and TRPM8 channels and nocifensive behavior in a rat model for dry eye
DA Bereiter, M Rahman, R Thompson… - … & visual science, 2018 - arvojournals.org
Purpose: Persistent ocular surface pain occurs in moderate to severe dry eye disease (DE);
however, the mechanisms that underlie this symptom remain uncertain. The aim of this study …
however, the mechanisms that underlie this symptom remain uncertain. The aim of this study …