The GATA family of transcription factors consists of six proteins (GATA1-6) which are
involved in a variety of physiological and pathological processes. GATA1/2/3 are required …

Congenital anomalies of the kidney and urinary tract (CAKUT) cover a wide range of
structural malformations that result from defects in the morphogenesis of the kidney and/or …

Abstract Adaptor protein-2 (AP2), a central component of clathrin-coated vesicles (CCVs), is
pivotal in clathrin-mediated endocytosis, which internalizes plasma membrane constituents …

Enhancers provide critical information directing cell-type-specific transcriptional programs,
regulated by binding of signal-dependent transcription factors and their associated …

There is increasing evidence that the numerous mechanisms that regulate cell differentiation
during normal development are also involved in tumorigenesis. In breast cancer …

Abstract GATA binding protein 3 (GATA3) is a transcriptional activator highly expressed by
the luminal epithelial cells in the breast. Here we did a meta-analysis of the available breast …

The WGATAR motif is a common nucleotide sequence found in the transcriptional regulatory
regions of numerous genes. In vertebrates, these motifs are bound by one of six factors …

GATA3, a transcription factor that regulates T lymphocyte differentiation and maturation, is
exclusively expressed in early stage well differentiated breast cancers but not in advanced …

GATA3 is an essential transcription factor that was first identified as a regulator of immune
cell function. In recent microarray analyses of human breast tumors, both normal breast …

The calcium-sensing receptor (CaSR) is a G-protein-coupled receptor that has an
extracellular bilobed venus flytrap domain (VFTD) predicted to contain five calcium (Ca2+) …