Trypanosoma cruzi, the causative agent of Chagas disease, presents wide genetic diversity.
Currently, six discrete typing units (DTUs), named TcI to TcVI, and a seventh one called …

Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important
parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of …

Background. One hundred years after the discovery of Chagas disease, it remains a major
neglected tropical disease. Chronic Chagas heart disease (cChHD) is the most severe …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Chagas disease caused by Trypanosoma cruzi is a complex disease that is endemic and an
important problem in public health in Latin America. The T. cruzi parasite is classified into six …

Trypanosoma cruzi, the agent of Chagas disease, can be subdivided into six discrete typing
units (DTUs), TcI, TcIIa, TcIIb, TcIIc, TcIId or TcIIe, each having distinct epidemiologically …

Background Trypanosoma cruzi, the causative agent of Chagas disease, displays significant
genetic variability revealed by six Discrete Typing Units (TcI-TcVI). In this pathology, oral …

Trypanosoma cruzi exhibits remarkable genetic heterogeneity. This is evident at the
nucleotide level but also structurally, in the form of karyotypic variation and DNA content …

Therapeutic failure of benznidazole (BZ) is widely documented in Chagas disease and has
been primarily associated with variations in the drug susceptibility of Trypanosoma cruzi …

Background Livestock trypanosomoses, caused by three species of the Trypanozoon
subgenus, Trypanosoma brucei brucei, T. evansi and T. equiperdum is widely distributed …