Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Objective To update the 2008 consensus statements for the diagnosis and management of
critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients …

We aimed to compare the effects of vitamin C, glucocorticoids, vitamin B1, combinations of
these drugs, and placebo or usual care on longer-term mortality in adults with sepsis or …

Bacterial infections are very common and represent one of the most important reasons of
progression of liver failure, development of liver-related complications, and mortality in …

Infections in Patients with Cirrhosis Patients with cirrhosis are at increased risk for serious
infections, including spontaneous bacterial peritonitis, multidrug-resistant infection, and …

Objective: This systematic review and meta-analysis addresses the efficacy and safety of
corticosteroids in critically ill patients with sepsis. Data Sources: We updated a …

Methods Prior to the conference, the organizing committee identified topics relevant to the
management of patients with ACLF. A diverse international panel representing multiple …

Sepsis remains a common, serious, and heterogeneous clinical entity that is difficult to
define adequately. Despite its importance as a public health problem, efforts to develop and …