Neuromodulation of neuronal circuits: back to the future
E Marder - Neuron, 2012 - cell.com
All nervous systems are subject to neuromodulation. Neuromodulators can be delivered as
local hormones, as cotransmitters in projection neurons, and through the general circulation …
local hormones, as cotransmitters in projection neurons, and through the general circulation …
Neuromodulation of circuits with variable parameters: single neurons and small circuits reveal principles of state-dependent and robust neuromodulation
Neuromodulation underlies many behavioral states and has been extensively studied in
small circuits. This has allowed the systematic exploration of how neuromodulatory …
small circuits. This has allowed the systematic exploration of how neuromodulatory …
Understanding circuit dynamics using the stomatogastric nervous system of lobsters and crabs
Studies of the stomatogastric nervous systems of lobsters and crabs have led to numerous
insights into the cellular and circuit mechanisms that generate rhythmic motor patterns. The …
insights into the cellular and circuit mechanisms that generate rhythmic motor patterns. The …
Global structure, robustness, and modulation of neuronal models
MS Goldman, J Golowasch, E Marder… - Journal of …, 2001 - Soc Neuroscience
The electrical characteristics of many neurons are remarkably robust in the face of changing
internal and external conditions. At the same time, neurons can be highly sensitive to …
internal and external conditions. At the same time, neurons can be highly sensitive to …
Multifunctional pattern-generating circuits
KL Briggman, WB Kristan Jr - Annu. Rev. Neurosci., 2008 - annualreviews.org
The ability of distinct anatomical circuits to generate multiple behavioral patterns is
widespread among vertebrate and invertebrate species. These multifunctional neuronal …
widespread among vertebrate and invertebrate species. These multifunctional neuronal …
Functional consequences of animal-to-animal variation in circuit parameters
How different are the neuronal circuits for a given behavior across individual animals? To
address this question, we measured multiple cellular and synaptic parameters in individual …
address this question, we measured multiple cellular and synaptic parameters in individual …
Cellular, synaptic and network effects of neuromodulation
E Marder, V Thirumalai - Neural Networks, 2002 - Elsevier
All network dynamics emerge from the complex interaction between the intrinsic membrane
properties of network neurons and their synaptic connections. Nervous systems contain …
properties of network neurons and their synaptic connections. Nervous systems contain …
Crustacean neuropeptides
AE Christie, EA Stemmler, PS Dickinson - Cellular and molecular life …, 2010 - Springer
Crustaceans have long been used for peptide research. For example, the process of
neurosecretion was first formally demonstrated in the crustacean X-organ–sinus gland …
neurosecretion was first formally demonstrated in the crustacean X-organ–sinus gland …
Multiple peptides converge to activate the same voltage-dependent current in a central pattern-generating circuit
AM Swensen, E Marder - Journal of Neuroscience, 2000 - Soc Neuroscience
The stomatogastric ganglion of the crab, Cancer borealis, is modulated by> 20 different
substances, including numerous neuropeptides. One of these peptides, proctolin, activates …
substances, including numerous neuropeptides. One of these peptides, proctolin, activates …
Animal-to-animal variability in motor pattern production in adults and during growth
Which features of network output are well preserved during growth of the nervous system
and across different preparations of the same size? To address this issue, we characterized …
and across different preparations of the same size? To address this issue, we characterized …