Neuromodulation of neuronal circuits: back to the future

E Marder - Neuron, 2012 - cell.com
All nervous systems are subject to neuromodulation. Neuromodulators can be delivered as
local hormones, as cotransmitters in projection neurons, and through the general circulation …

Neuromodulation of circuits with variable parameters: single neurons and small circuits reveal principles of state-dependent and robust neuromodulation

E Marder, T O'Leary, S Shruti - Annual review of neuroscience, 2014 - annualreviews.org
Neuromodulation underlies many behavioral states and has been extensively studied in
small circuits. This has allowed the systematic exploration of how neuromodulatory …

Understanding circuit dynamics using the stomatogastric nervous system of lobsters and crabs

E Marder, D Bucher - Annu. Rev. Physiol., 2007 - annualreviews.org
Studies of the stomatogastric nervous systems of lobsters and crabs have led to numerous
insights into the cellular and circuit mechanisms that generate rhythmic motor patterns. The …

Global structure, robustness, and modulation of neuronal models

MS Goldman, J Golowasch, E Marder… - Journal of …, 2001 - Soc Neuroscience
The electrical characteristics of many neurons are remarkably robust in the face of changing
internal and external conditions. At the same time, neurons can be highly sensitive to …

Multifunctional pattern-generating circuits

KL Briggman, WB Kristan Jr - Annu. Rev. Neurosci., 2008 - annualreviews.org
The ability of distinct anatomical circuits to generate multiple behavioral patterns is
widespread among vertebrate and invertebrate species. These multifunctional neuronal …

Functional consequences of animal-to-animal variation in circuit parameters

JM Goaillard, AL Taylor, DJ Schulz, E Marder - Nature neuroscience, 2009 - nature.com
How different are the neuronal circuits for a given behavior across individual animals? To
address this question, we measured multiple cellular and synaptic parameters in individual …

Cellular, synaptic and network effects of neuromodulation

E Marder, V Thirumalai - Neural Networks, 2002 - Elsevier
All network dynamics emerge from the complex interaction between the intrinsic membrane
properties of network neurons and their synaptic connections. Nervous systems contain …

Crustacean neuropeptides

AE Christie, EA Stemmler, PS Dickinson - Cellular and molecular life …, 2010 - Springer
Crustaceans have long been used for peptide research. For example, the process of
neurosecretion was first formally demonstrated in the crustacean X-organ–sinus gland …

Multiple peptides converge to activate the same voltage-dependent current in a central pattern-generating circuit

AM Swensen, E Marder - Journal of Neuroscience, 2000 - Soc Neuroscience
The stomatogastric ganglion of the crab, Cancer borealis, is modulated by> 20 different
substances, including numerous neuropeptides. One of these peptides, proctolin, activates …

Animal-to-animal variability in motor pattern production in adults and during growth

D Bucher, AA Prinz, E Marder - Journal of Neuroscience, 2005 - Soc Neuroscience
Which features of network output are well preserved during growth of the nervous system
and across different preparations of the same size? To address this issue, we characterized …