Targeting arachidonic acid pathway by natural products for cancer prevention and therapy

NS Yarla, A Bishayee, G Sethi, P Reddanna… - Seminars in cancer …, 2016 - Elsevier
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

[HTML][HTML] Pharmacological and therapeutic potential of myristicin: A literature review

EF Seneme, DC Dos Santos, EMR Silva, YEM Franco… - Molecules, 2021 - mdpi.com
Natural products have been used by humanity for many centuries to treat various illnesses
and with the advancement of technology, it became possible to isolate the substances …

From natural sources to synthetic derivatives: The allyl motif as a powerful tool for fragment-based design in cancer treatment

N Astrain-Redin, C Sanmartin… - Journal of Medicinal …, 2023 - ACS Publications
Since the beginning of history, natural products have been an abundant source of bioactive
molecules for the treatment of different diseases, including cancer. Many allyl derivatives …

[HTML][HTML] A review on anti-inflammatory activity of phenylpropanoids found in essential oils

RCS Sá, L Nalone Andrade… - Molecules, 2014 - mdpi.com
The search for alternative drugs capable of disrupting the inflammatory process has become
an important issue in scientific research, especially with reference to the use of natural …

[HTML][HTML] Myristicin and elemicin: potentially toxic alkenylbenzenes in food

ME Götz, B Sachse, B Schäfer, A Eisenreich - Foods, 2022 - mdpi.com
Alkenylbenzenes represent a group of naturally occurring substances that are synthesized
as secondary metabolites in various plants, including nutmeg and basil. Many of the …

In vitro toxicological evaluation of essential oils and their main compounds used in active food packaging: A review

M Llana-Ruiz-Cabello, S Pichardo, S Maisanaba… - Food and Chemical …, 2015 - Elsevier
Essential oils (EOs) and their main constituent compounds have been extensively
investigated due to their application in the food industry for improving the shelf life of …

[HTML][HTML] Anti-inflammatory effect of myristicin on RAW 264.7 macrophages stimulated with polyinosinic-polycytidylic acid

JY Lee, W Park - Molecules, 2011 - mdpi.com
Myristicin (1-allyl-5-methoxy-3, 4-methylenedioxybenzene) is an active aromatic compound
found in nutmeg (the seed of Myristica fragrans), carrot, basil, cinnamon, and parsley …

New advances in active packaging incorporated with essential oils or their main components for food preservation

S Maisanaba, M Llana-Ruiz-Cabello… - Food Reviews …, 2017 - Taylor & Francis
The food industry is developing new packaging systems (active packaging) through the
incorporation of essential oils or their main compounds into the films. This could confer them …

Relevant essential oil components: a minireview on increasing applications and potential toxicity

C Fuentes, A Fuentes, JM Barat… - … mechanisms and methods, 2021 - Taylor & Francis
Phenolic compounds carvacrol, thymol, eugenol, and vanillin are four of the most thoroughly
investigated essential oil components given their relevant biological properties. These …

Targeting endoplasmic reticulum stress, Nrf-2/HO-1, and NF-κB by myristicin and its role in attenuation of ulcerative colitis in rats

HMIA El-Fadl, MFA Mohamed - Life Sciences, 2022 - Elsevier
Aims Ulcerative colitis (UC) is characterized by the up-regulation of pro-inflammatory
mediators, apoptotic signals, and oxidative stress that can lead to an increased risk of …