Reactive oxygen species (ROS) in biological systems are transient but essential molecules
that are generated and eliminated by a complex set of delicately balanced molecular …

Abstract When p62/Sequestosome‐1 binds to a ubiquitinated protein, it undergoes liquid–
liquid phase separation (LLPS) and forms a membraneless organelle, p62 body. There are …

Summary p62 is a well-characterized autophagy receptor that recognizes and sequesters
specific cargoes into autophagosomes for degradation. p62 promotes the assembly and …

Phthalates as a large group of environmental pollutants are used primarily as plasticizers
and solvents, which have become a growing problem worldwide. Epidemiological results …

The ubiquity of microplastics increases the exposure risks and health threats to humans. In
this study, rat basophilic leukemia (RBL-2H3) cells were exposed to polystyrene particles …

Ferroptosis is characterized by the accumulation of iron and lipid peroxidation products,
which regulates physiological and pathological processes in numerous organs and tissues …

NRF2 is an important regulatory transcription factor involved in tumor immunity and
tumorigenesis. In this study, we firstly identified that FKBP4/NR3C1 axis was a novel …

p62/Sequestosome‐1 (SQSTM1) is a selective autophagy receptor that recruits and delivers
intracellular substrates for bulk clearance through the autophagy lysosomal pathway …

Cellular zoning or partitioning is critical in preventing macromolecules from random diffusion
and orchestrating the spatiotemporal dynamics of biochemical reactions. Along with …

Physiological concentrations of reactive oxygen species (ROS) play vital roles in various
normal cellular processes, whereas excessive ROS generation is central to disease …