In the field of drug discovery, isoxazole is a five-membered heterocyclic moiety commonly
found in many commercially available drugs. In view of their enormous significance, it is …

Mental disorders are neuropsychiatric conditions that are marked by unusual or irregular
thinking, feelings, or behavior, and lead to distress and/or impaired functions. Major …

In this work, a novel synthetic methodology for the one-pot preparation of isoxazoles directly
from the reaction of calcium carbide with aldoximes is reported. Calcium carbide acts as a …

The results of the study on reactions of halogenoximes bearing (protected) functional groups
or fluorinated substituents with various phosphorus-containing dipolarophiles are described …

A comprehensive study on the synthesis of 5-fluoroalkyl-substituted isoxazoles starting from
functionalized halogenoximes is reported. One-pot metal-free [3+ 2] cycloaddition of CF3 …

A highly efficient multigram synthesis of spirocyclic and fused isoxazoline building blocks is
described. Isoxazoline‐3‐carboxylates were synthesized via a regioselective 1, 3‐dipolar …

A novel synthetic path to 1, 3‐disubstituted pyrazoles and their deuterated derivatives was
developed. It is based on the reaction of vinyl ethers with hydrazonoyl chlorides in the …

A solvent‐free nano‐titania‐supported sulfonic acid [nano‐TiO2‐SO3H (n‐TSA)] catalyzed
approach has been developed for the synthesis of pharmaceutically interesting new hybrids …

Various primary alcohols were smoothly transformed into 3-aryl-and 3-alkylisoxazoles in
good yields in one pot by successive treatment with PhI (OAc) 2 in the presence of TEMPO …

In this paper, a simple and efficient synthetic route for the preparation of new heterocyclic
amino acid derivatives containing azetidine and oxetane rings was described. The starting …