Carrageenan (CGN) has been used as a safe food additive for several decades. Confusion
over nomenclature, basic CGN chemistry, type of CGN tested, interspecies biology, and …

The enzyme N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) was originally
identified as a lysosomal enzyme which was deficient in Mucopolysaccharidosis VI (MPS VI; …

Heparosan is an acidic polysaccharide natural product, which serves as the critical
precursor in heparin biosynthesis and in the chemoenzymatic synthesis of bioengineered …

The pathogenesis of lung disease in cystic fibrosis is characterised by decreased airway
surface liquid volume and subsequent failure of normal mucociliary clearance. Mucus within …

In utero ethanol exposure causes fetal alcohol spectrum disorders, associated with reduced
brain plasticity; the mechanisms of these effects are not well understood, particularly with …

Background: The enzyme arylsulfatase B (ARSB; N-acetylgalactosamine-4-sulfatase)
degrades chondroitin-4-sulfate (C4S) and is reduced in malignant colonic and mammary …

In the lung, glycosaminoglycans (GAGs) are dispersed in the extracellular matrix (ECM)
occupying the interstitial space between the capillary endothelium and the alveolar …

This report presents evidence of 1) a role for arylsulfatase B (ARSB; N-acetylgalactosamine-
4-sulfatase) in mediating intracellular oxygen signaling; 2) replication between the effects of …

Abstract Arylsulfatase B (N-acetylgalactosamine-4-sulfatase; ARSB) removes 4-sulfate
groups from chondroitin-4-sulfate (C4S) and dermatan sulfate and is required for their …

Exposure to low concentration of the common food additive carrageenan (10 mg/L) for only
six days led to glucose intolerance and insulin resistance in the C57BL/6J mouse. Longer …