Advances in decomposing complex metabolite mixtures using substructure-and network-based computational metabolomics approaches

MA Beniddir, KB Kang, G Genta-Jouve, F Huber… - Natural product …, 2021 - pubs.rsc.org
Covering: up to the end of 2020 Recently introduced computational metabolome mining
tools have started to positively impact the chemical and biological interpretation of …

Accelerating metabolite identification in natural product research: toward an ideal combination of liquid chromatography–high-resolution tandem mass spectrometry …

JL Wolfender, JM Nuzillard, JJJ Van Der Hooft… - Analytical …, 2018 - ACS Publications
Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …

Real-time prediction of 1 H and 13 C chemical shifts with DFT accuracy using a 3D graph neural network

Y Guan, SVS Sowndarya, LC Gallegos, PCS John… - Chemical …, 2021 - pubs.rsc.org
Nuclear magnetic resonance (NMR) is one of the primary techniques used to elucidate the
chemical structure, bonding, stereochemistry, and conformation of organic compounds. The …

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

JB McAlpine, SN Chen, A Kutateladze… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …

Computer assisted structure elucidation (CASE): current and future perspectives

M Elyashberg, D Argyropoulos - Magnetic Resonance in …, 2021 - Wiley Online Library
The first efforts for the development of methods for Computer‐Assisted Structure Elucidation
(CASE) were published more than 50 years ago. CASE expert systems based on one …

MixONat, a Software for the Dereplication of Mixtures Based on 13C NMR Spectroscopy

A Bruguière, S Derbré, J Dietsch, J Leguy… - Analytical …, 2020 - ACS Publications
Whether chemists or biologists, researchers dealing with metabolomics require tools to
decipher complex mixtures. As a part of metabolomics and initially dedicated to identifying …

Parallel nuclear magnetic resonance spectroscopy

Ē Kupče, L Frydman, AG Webb, JRJ Yong… - Nature Reviews …, 2021 - nature.com
Nuclear magnetic resonance (NMR) spectroscopy is a principal analytical technique used
for the structure elucidation of molecules. This Primer covers different approaches to …

[HTML][HTML] The repository chemotion: infrastructure for sustainable research in chemistry

P Tremouilhac, CL Lin, PC Huang… - … (International ed. in …, 2020 - ncbi.nlm.nih.gov
The repository Chemotion provides solutions for current challenges to store research data in
a feasible manner. A main advantage of Chemotion is the comprehensive functionality …

An automated framework for NMR chemical shift calculations of small organic molecules

Y Yesiltepe, JR Nuñez, SM Colby, DG Thomas… - Journal of …, 2018 - Springer
When using nuclear magnetic resonance (NMR) to assist in chemical identification in
complex samples, researchers commonly rely on databases for chemical shift spectra …

[PDF][PDF] NFDI4Chem-towards a national research data infrastructure for chemistry in Germany

C Steinbeck, O Koepler, F Bach… - Research ideas and …, 2020 - riojournal.com
The vision of NFDI4Chem is the digitalisation of all key steps in chemical research to support
scientists in their efforts to collect, store, process, analyse, disclose and re-use research …