Molecular dynamics simulation studies on the aggregation of amyloid-β peptides and their disaggregation by ultrasonic wave and infrared laser irradiation
Alzheimer's disease is understood to be caused by amyloid fibrils and oligomers formed by
aggregated amyloid-β (Aβ) peptides. This review article presents molecular dynamics (MD) …
aggregated amyloid-β (Aβ) peptides. This review article presents molecular dynamics (MD) …
The evolution of temperature and desiccation-related protein families in Tardigrada reveals a complex acquisition of extremotolerance
Tardigrada is an ecdysozoan lineage famed for its resilience. Tardigrades can tolerate high
doses of radiation, low-oxygen environments, desiccation, and both high and low …
doses of radiation, low-oxygen environments, desiccation, and both high and low …
Helicity of a tardigrade disordered protein contributes to its protective function during desiccation
To survive extreme drying (anhydrobiosis), many organisms, spanning every kingdom of life,
accumulate intrinsically disordered proteins (IDPs). For decades, the ability of anhydrobiosis …
accumulate intrinsically disordered proteins (IDPs). For decades, the ability of anhydrobiosis …