[HTML][HTML] Non-Brownian diffusion in lipid membranes: Experiments and simulations

R Metzler, JH Jeon, AG Cherstvy - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

Macromolecular Crowding and DNA: Bridging the Gap between In Vitro and In Vivo

D Collette, D Dunlap, L Finzi - International Journal of Molecular Sciences, 2023 - mdpi.com
The cellular environment is highly crowded, with up to 40% of the volume fraction of the cell
occupied by various macromolecules. Most laboratory experiments take place in dilute …

Anomalous, non-Gaussian tracer diffusion in crowded two-dimensional environments

SK Ghosh, AG Cherstvy, DS Grebenkov… - New Journal of …, 2016 - iopscience.iop.org
A topic of intense current investigation pursues the question of how the highly crowded
environment of biological cells affects the dynamic properties of passively diffusing particles …

Facilitation of polymer looping and giant polymer diffusivity in crowded solutions of active particles

J Shin, AG Cherstvy, WK Kim, R Metzler - New Journal of Physics, 2015 - iopscience.iop.org
We study the dynamics of polymer chains in a bath of self-propelled particles (SPP) by
extensive Langevin dynamics simulations in a two-dimensional model system. Specifically …

[HTML][HTML] Seaweed polysaccharides as macromolecular crowding agents

A De Pieri, S Rana, S Korntner, DI Zeugolis - International Journal of …, 2020 - Elsevier
Abstract Development of mesenchymal stem cell-based tissue engineered implantable
devices requires prolonged in vitro culture for the development of a three-dimensional …

Shape-dependent macromolecular crowding on the thermodynamics and microsecond conformational dynamics of protein unfolding revealed at the single-molecule …

N Das, P Sen - The Journal of Physical Chemistry B, 2020 - ACS Publications
One of the main differences in the intercellular environment compared to the laboratory
condition is the presence of macromolecular crowders of various compositions, sizes, and …

Particle dynamics and transport enhancement in a confined channel with position-dependent diffusivity

Y Li, R Mei, Y Xu, J Kurths, J Duan… - New Journal of …, 2020 - iopscience.iop.org
This work focuses on the dynamics of particles in a confined geometry with position-
dependent diffusivity, where the confinement is modelled by a periodic channel consisting of …

Chain reconfiguration in active noise

N Samanta, R Chakrabarti - Journal of Physics A: Mathematical …, 2016 - iopscience.iop.org
In a typical single molecule experiment, the dynamics of an unfolded protein is studied by
determining the reconfiguration time using long-range Förster resonance energy transfer …

Polymer looping is controlled by macromolecular crowding, spatial confinement, and chain stiffness

J Shin, AG Cherstvy, R Metzler - ACS Macro Letters, 2015 - ACS Publications
We study by extensive computer simulations the looping characteristics of linear polymers
with varying persistence length inside a spherical cavity in the presence of macromolecular …

Tracer diffusion in a sea of polymers with binding zones: mobile vs. frozen traps

N Samanta, R Chakrabarti - Soft matter, 2016 - pubs.rsc.org
We use molecular dynamics simulations to investigate the tracer diffusion in a sea of
polymers with specific binding zones for the tracer. These binding zones act as traps. Our …