Progesterone and its synthetic analogues, progestins, participate in the regulation of cell
differentiation, proliferation and cell cycle progression. Progestins are usually applied for …

Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a heme-binding
protein that has been implicated in a wide range of cell and tissue functions, including …

Cancer cells usually show different metabolic patterns compared with healthy cells due to
the reprogramming of metabolic processes. The process of lipid metabolism undergoes …

Progesterone receptor membrane component (PGRMC) proteins play important roles in
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …

Simple Summary Progesterone receptor membrane component 1 (PGRMC1) and epidermal
growth factor receptor (EGFR) are highly expressed in various cancers. Here, we first …

Heterotopic ossification (HO) is the formation of abnormal mature lamellar bone in extra-
skeletal sites, including soft tissues and joints, which result in high rates of disability. The …

Breast cancer, as the most common malignancy, is the second leading cause of cancer‐
related death in women. One of the kelch family member ENC1 is involved in various …

Lung cancer (LC) is one of the most incident malignancies and a leading cause of cancer
mortality worldwide. Common tumorigenic drivers of LC mainly include genetic alterations of …

Although olanzapine (OLZ) remains one of the most efficacious antipsychotic medications
for the treatment of schizophrenia, there are significant tolerability issues related to its …

Progesterone Receptor Membrane Component 1 (PGRMC1) is a tumour-promoting factor in
several types of cancer but its role in brain tumours is poorly characterized thus far. Our …