The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

Neural plasticity, a fundamental mechanism of neuronal adaptation, is disrupted in
depression. The changes in neural plasticity induced by stress and other negative stimuli …

Background Perinatal maternal depression is a serious health concern with potential lasting
negative consequences for children. Prenatal depression is associated with altered brain …

A little more than a decade ago the concept of a preschooler with depression and/or anxiety
disorders was not taken seriously. Many people think that early childhood is a time of …

Background Studies investigating the relationship between exposure to air pollution and
brain development using magnetic resonance images are emerging. However, most studies …

The unique neuroanatomical underpinnings of internalizing symptoms and impulsivity
during childhood are not well understood. In this study, we examined associations of brain …

Studies of early life stress (ELS) demonstrate the long-lasting effects of acute and chronic
stress on developmental trajectories. Such experiences can become biologically …

Alterations in functional brain lateralization, often indicated by an increased prevalence of
left-and/or mixed-handedness, have been demonstrated in several psychiatric and …

Importance The trajectory of cortical gray matter development in childhood has been
characterized by early neurogenesis and volume increase, peaking at puberty followed by …

BACKGROUND Although several epidemiological studies have assessed the association
between air pollution exposure during early life and child neurological development, it is yet …