Amyloid proteins can aggregate into insoluble fibrils and form amyloid deposits in the
human brain, which is the hallmark of many neurodegenerative diseases. Promising …

The pursuit of a novel structural motif that can shed light on the key functional attributes is a
primary focus in the study of protein folding disorders. Decades of research on Alzheimer's …

Amyloidosis of amyloid-β (Aβ) triggers a cascade of events, leading to oxidative damage
and neuronal death. Therefore, inhibiting Aβ amyloidosis or disrupting the matured fibrils is …

The self-assembly of peptides forming various micro to nanostructures has several
applications in nanobiotechnology. β-Sheet based peptides are well known as they are …

Fibril formation of amyloid β (Aβ) peptides is one of the key molecular events connected to
Alzheimer's disease. The pathway of formation and mechanism of action of Aβ aggregates in …

Amyloid proteins and peptides play a pivotal role in the etiology of various
neurodegenerative diseases, including Alzheimer's disease (AD). Synthetically designed …

Amyloidogenesis, with its multifaceted nature spanning from peptide self-assembly to
membrane-mediated structural transitions, presents a significant challenge for the …

Amyloid-β (A β) fibrils are the characteristic hallmark of Alzheimer's disease (AD), and most
drug development approaches for AD are focused on preventing and reversing the …

Alzheimer's disease (AD) is a common neurodegenerative disorder. The most recognized
disease pathology is the Amyloid-β (Aβ) cascade hypothesis which states that the …

Amyloid-β (Aβ) fibrils are the characteristic hallmark of Alzheimer's disease (AD), and most
drug development approaches for AD are focused on preventing and reversing the …