Chemistry and biological activities of 1, 2, 4-triazolethiones—antiviral and anti-infective drugs

AA Aly, A A. Hassan, MM Makhlouf, S Bräse - Molecules, 2020 - mdpi.com
Mercapto-substituted 1, 2, 4-triazoles are very interesting compounds as they play an
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …

Tandem Reactions of Ynones: via Conjugate Addition of Nitrogen‐, Carbon‐, Oxygen‐, Boron‐, Silicon‐, Phosphorus‐, and Sulfur‐Containing Nucleophiles

Y Li, J Yu, Y Bi, G Yan, D Huang - Advanced Synthesis & …, 2019 - Wiley Online Library
Ynones are widely used in organic synthesis. Their great success is rooted in their multiple
functional groups. This review focus on advance of ynones in published in the decade 2009 …

Fused bicyclic 1, 2, 4‐triazoles with one extra sulfur atom: Synthesis, properties, and biological activity

MV Slivka, NI Korol, MM Fizer - Journal of Heterocyclic …, 2020 - Wiley Online Library
Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

Recent advances in 1, 2, 4-triazolo [1, 5-a] pyrimidine chemistry

G Fischer - Advances in Heterocyclic Chemistry, 2019 - Elsevier
The review deals with the pharmaceutically and agrochemically important group of 1, 2, 4-
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …

Discovery of ( ±)-3-(1H-pyrazol-1-yl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral …

PC Jilloju, L Persoons, SK Kurapati, D Schols… - Molecular Diversity, 2022 - Springer
A new series of (±)-(3-(3, 5-dimethyl-1 H-pyrazol-1-yl)-6-phenyl-6, 7-dihydro-5 H-[1, 2, 4]
triazolo [3, 4-b][1, 3, 4] thiadiazin-7-yl)(phenyl) methanones were efficiently synthesized …

Visible-light-mediated regioselective synthesis of novel thiazolo [3, 2-b][1, 2, 4] triazoles: advantageous synthetic application of aqueous conditions

R Aggarwal, M Hooda, P Kumar… - Organic & Biomolecular …, 2022 - pubs.rsc.org
From a green chemistry perspective, sustainable irradiation as the power source and water
as the solvent have certainly grabbed the attention of chemists in recent times because their …

The vital use of isocyanide-based multicomponent reactions (MCR) in chemical synthesis

RL Mohlala, EM Coyanis - Physical Sciences Reviews, 2024 - degruyter.com
Multicomponent (MCRs) reactions are classified as one-pot reaction where more than two
starting materials are employed to form a single product that contains the building blocks of …

Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold

R Aggarwal, M Hooda, P Kumar, G Sumran - Topics in Current Chemistry, 2022 - Springer
The present review article strives to compile the latest synthetic approaches for the synthesis
of triazolothiadiazine and its derivatives, along with their diverse pharmacological activities …

Recent progress in the synthesis of thiazolo[3,2-b][1,2,4]triazoles (microreview)

NI Korol, MV Slivka - Chemistry of Heterocyclic Compounds, 2017 - Springer
A summary of the most recent approaches toward synthesis of thiazolo [3, 2-b][1, 2, 4]
triazole system is reported. The microreview covers the latest selected examples on the …

[HTML][HTML] Synthetic Methods and Pharmacological Potentials of Triazolothiadiazines: A Review

MS Mostafa, IAM Radini, NMA El-Rahman, RE Khidre - Molecules, 2024 - mdpi.com
This review article examines the synthetic pathways for triazolothiadiazine derivatives, such
as triazolo [3, 4-b] thiadiazines, triazolo [5, 1-b] thiadiazines, and triazolo [4, 3-c] …