Organic chemistry is continually evolving to improve the syntheses of value added and
bioactive compounds. Through this progression, a concomitant advancement in laboratory …

Cycloparaphenylenes (CPPs) have attracted significant attention from theoretical, synthetic,
supramolecular and material chemists owing to their aesthetical structures. Since Jasti and …

The direct C–H metallation of tetrahydrofuran (THF) to generate α-anionic THF is one of the
most straightforward methods for the functionalization of THF. However, the stability of THF …

Ibuprofen was prepared from an inactive and inexpensive p‐xylene by three‐step flow
functionalizations through chemoselective metalations of benzyl positions in sequence …

The rapid and precise fabrication of multiscale supramolecular assemblies using
micro/nanofluidic techniques has emerged as a dynamic area of research in supramolecular …

Reported is the electrophilic amination of functional organolithium intermediates with well‐
designed aminating reagents under mild reaction conditions using flow microreactors. The …

We herein report an atom-economic flow approach to the selective and sequential mono-, di-
, and tri-functionalizations of unactivated hydrosilanes via serial organolithium reactions …

High‐resolution 3D‐printed stainless steel metal microreactors (3D‐PMRs) with different
cross‐sectional geometry are fabricated to control ultrafast intramolecular rearrangement …

The synthesis of [n] cycloparaphenylenes ([n] CPPs) and similar nanohoops is usually
based on combining building blocks to a macrocyclic precursor, which is then aromatized in …

Continuous-flow microreactors enable ultrafast chemistry; however, their small capacity
restricts industrial-level productivity of pharmaceutical compounds. In this work, scale-up …