A guide to chemokines and their receptors

CE Hughes, RJB Nibbs - The FEBS journal, 2018 - Wiley Online Library
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …

Mechanoreciprocity in cell migration

S Van Helvert, C Storm, P Friedl - Nature cell biology, 2018 - nature.com
Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

E Peranzoni, J Lemoine, L Vimeux… - Proceedings of the …, 2018 - National Acad Sciences
In a large proportion of cancer patients, CD8 T cells are excluded from the vicinity of cancer
cells. The inability of CD8 T cells to reach tumor cells is considered an important mechanism …

Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

The extracellular matrix in skin inflammation and infection

K Pfisterer, LE Shaw, D Symmank… - Frontiers in cell and …, 2021 - frontiersin.org
The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …

Neutrophil migration in infection and wound repair: going forward in reverse

S De Oliveira, EE Rosowski… - Nature Reviews …, 2016 - nature.com
Neutrophil migration and its role during inflammation has been the focus of increased
interest in the past decade. Advances in live imaging and the use of new model systems …

Leukocyte migration into inflamed tissues

S Nourshargh, R Alon - Immunity, 2014 - cell.com
Leukocyte migration through activated venular walls is a fundamental immune response that
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …

Neutrophils self-limit swarming to contain bacterial growth in vivo

K Kienle, KM Glaser, S Eickhoff, M Mihlan, K Knöpper… - Science, 2021 - science.org
INTRODUCTION The collective behavior of cells and insects often relies on self-organizing
processes. By releasing attractant signals, a few individuals can initiate the accumulation …

Tertiary lymphoid structures, drivers of the anti‐tumor responses in human cancers

MC Dieu‐Nosjean, NA Giraldo, H Kaplon… - Immunological …, 2016 - Wiley Online Library
The characterization of the microenvironment of human tumors led to the description of
tertiary lymphoid structures (TLS) characterized by mature dendritic cells in a T‐cell zone …

Neutrophils in acute inflammation: current concepts and translational implications

A Margraf, CA Lowell, A Zarbock - Blood, The Journal of the …, 2022 - ashpublications.org
Modulation of neutrophil recruitment and function is crucial for targeting inflammatory cells to
sites of infection to combat invading pathogens while, at the same time, limiting host tissue …