[HTML][HTML] The basic immunology of asthma

H Hammad, BN Lambrecht - Cell, 2021 - cell.com
In many asthmatics, chronic airway inflammation is driven by IL-4-, IL-5-, and IL-13-
producing Th2 cells or ILC2s. Type 2 cytokines promote hallmark features of the disease …

[HTML][HTML] Eosinophils in health and disease: a state-of-the-art review

ME Wechsler, A Munitz, SJ Ackerman, MG Drake… - Mayo Clinic …, 2021 - Elsevier
Eosinophils play a homeostatic role in the body's immune responses. These cells are
involved in combating some parasitic, bacterial, and viral infections and certain cancers and …

The role of lung and gut microbiota in the pathology of asthma

W Barcik, RCT Boutin, M Sokolowska, BB Finlay - Immunity, 2020 - cell.com
Asthma is a common chronic respiratory disease affecting more than 300 million people
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …

Advances and recent developments in asthma in 2020

L Cevhertas, I Ogulur, DJ Maurer, D Burla, M Ding… - Allergy, 2020 - Wiley Online Library
In this review, we discuss recent publications on asthma and review the studies that have
reported on the different aspects of the prevalence, risk factors and prevention, mechanisms …

The role of peripheral blood eosinophil counts in COVID‐19 patients

G Xie, F Ding, L Han, D Yin, H Lu, M Zhang - Allergy, 2021 - Wiley Online Library
Abstract Background Coronavirus disease 2019 (COVID‐19) emerged in Wuhan city and
rapidly spread globally outside China. We aimed to investigate the role of peripheral blood …

Anti-alarmins in asthma: targeting the airway epithelium with next-generation biologics

CM Porsbjerg, A Sverrild, CM Lloyd… - European …, 2020 - Eur Respiratory Soc
Monoclonal antibody therapies have significantly improved treatment outcomes for patients
with severe asthma; however, a significant disease burden remains. Available biologic …

Impact of allergic rhinitis and asthma on COVID-19 infection, hospitalization, and mortality

J Ren, W Pang, Y Luo, D Cheng, K Qiu, Y Rao… - The Journal of Allergy …, 2022 - Elsevier
Background It remains unclear if patients with allergic rhinitis (AR) and/or asthma are
susceptible to corona virus disease 2019 (COVID-19) infection, severity, and mortality …

Considerations on biologicals for patients with allergic disease in times of the COVID‐19 pandemic: an EAACI statement

A Vultaggio, I Agache, CA Akdis, M Akdis, S Bavbek… - Allergy, 2020 - Wiley Online Library
The outbreak of the SARS‐CoV‐2‐induced coronavirus disease 2019 (COVID‐19)
pandemic re‐shaped doctor‐patient interaction and challenged capacities of healthcare …

[HTML][HTML] Relationship between blood eosinophil levels and COVID-19 mortality

B Yan, J Yang, Y Xie, X Tang - World Allergy Organization Journal, 2021 - Elsevier
Objectives A novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2), is causing the worldwide coronavirus disease 2019 (COVID-19) outbreak with high …

The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice

NL Diny, B Schonfeldova, M Shapiro… - Journal of Experimental …, 2022 - rupress.org
Eosinophils are potent sources of inflammatory and toxic mediators, yet they reside in large
numbers in the healthy intestine without causing tissue damage. We show here that …