[HTML][HTML] Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms

M Kundakovic, D Rocks - Frontiers in neuroendocrinology, 2022 - Elsevier
Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

Effect of estrous cycle on behavior of females in rodent tests of anxiety

TA Lovick, H Zangrossi Jr - Frontiers in psychiatry, 2021 - frontiersin.org
Anxiety disorders are more prevalent in women than in men. In women the menstrual cycle
introduces another variable; indeed, some conditions eg, premenstrual syndrome, are …

[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Why are women so vulnerable to anxiety, trauma-related and stress-related disorders? The potential role of sex hormones

SH Li, BM Graham - The Lancet Psychiatry, 2017 - thelancet.com
Increased prevalence, severity, and burden of anxiety, trauma-related and stress-related
disorders in women compared with men has been well documented. Evidence from a variety …

Oestradiol as a neuromodulator of learning and memory

LR Taxier, KS Gross, KM Frick - Nature Reviews Neuroscience, 2020 - nature.com
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

The role of associative fear and avoidance learning in anxiety disorders: Gaps and directions for future research

A Pittig, M Treanor, RT LeBeau, MG Craske - … & Biobehavioral Reviews, 2018 - Elsevier
Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Sex differences in anxiety disorders: interactions between fear, stress, and gonadal hormones

LY Maeng, MR Milad - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “SBN 2014”. Women are more vulnerable to stress-and
fear-based disorders, such as anxiety and post-traumatic stress disorder. Despite the …

Sex differences in antidepressant efficacy

TA LeGates, MD Kvarta, SM Thompson - Neuropsychopharmacology, 2019 - nature.com
Sex differences have been observed across many psychiatric diseases, especially mood
disorders. For major depression, the most prevalent psychiatric disorder, females show a …

A review on sex differences in processing emotional signals

ME Kret, B De Gelder - Neuropsychologia, 2012 - Elsevier
Interest in sex-related differences in psychological functioning has again come to the
foreground with new findings about their possible functional basis in the brain. Sex …

Fear extinction as a model for translational neuroscience: ten years of progress

MR Milad, GJ Quirk - Annual review of psychology, 2012 - annualreviews.org
The psychology of extinction has been studied for decades. Approximately 10 years ago,
however, there began a concerted effort to understand the neural circuits of extinction of fear …