Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …

Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND)
comprise a group of illnesses marked by memory and behavioral dysfunction that can occur …

Alzheimer's disease and cerebral small vessel disease are the two leading causes of
cognitive decline and dementia and coexist in most memory clinic patients. White matter …

White matter hyperintensities (WMH), frequently seen in older adults, are usually considered
vascular lesions, and participate in the vascular contribution to cognitive impairment and …

Cognitive deficits in Alzheimer's disease, specifically amnestic (memory dominant) deficits,
are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus …

Convolutional neural networks have achieved state-of-the-art performance for white matter
(WM) tract segmentation based on diffusion magnetic resonance imaging (dMRI). However …

Background and Objectives Alzheimer disease (AD) is primarily associated with
accumulations of amyloid plaques and tau tangles in gray matter, however, it is now …

Several studies have shown white matter (WM) abnormalities in Alzheimer's disease (AD)
using diffusion tensor imaging (DTI). Nonetheless, robust characterization of WM changes …

Objective To investigate the correlation between specific fiber tracts and grip strength and
cognitive function in patients with Alzheimer's disease (AD) by fixel-based analysis (FBA) …