[HTML][HTML] Atrial and brain natriuretic peptides: Hormones secreted from the heart

Y Nakagawa, T Nishikimi, K Kuwahara - Peptides, 2019 - Elsevier
The natriuretic peptide family consists of three biologically active peptides: atrial natriuretic
peptide (ANP), brain (or B-type) natriuretic peptide (BNP), and C-type natriuretic peptide …

The natriuretic peptide system in heart failure: Diagnostic and therapeutic implications

K Kuwahara - Pharmacology & therapeutics, 2021 - Elsevier
Natriuretic peptides, which are activated in heart failure, play an important cardioprotective
role. The most notable of the cardioprotective natriuretic peptides are atrial natriuretic …

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

D Fan, A Takawale, J Lee, Z Kassiri - Fibrogenesis & tissue repair, 2012 - Springer
Fibroblasts comprise the largest cell population in the myocardium. In heart disease, the
number of fibroblasts is increased either by replication of the resident myocardial fibroblasts …

The natriuretic peptides system in the pathophysiology of heart failure: from molecular basis to treatment

M Volpe, M Carnovali, V Mastromarino - Clinical Science, 2016 - portlandpress.com
After its discovery in the early 1980s, the natriuretic peptide (NP) system has been
extensively characterized and its potential influence in the development and progression of …

Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications

LR Potter, AR Yoder, DR Flora, LK Antos… - … generators, effectors and …, 2009 - Springer
Natriuretic peptides are a family of three structurally related hormone/paracrine factors. Atrial
natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are secreted from the cardiac …

Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions

LR Potter, S Abbey-Hosch, DM Dickey - Endocrine reviews, 2006 - academic.oup.com
Natriuretic peptides are a family of structurally related but genetically distinct
hormones/paracrine factors that regulate blood volume, blood pressure, ventricular …

Role of oxidative stress in cardiac hypertrophy and remodeling

E Takimoto, DA Kass - Hypertension, 2007 - Am Heart Assoc
cellular apoptosis signaling kinase-1, a redox-sensitive kinase upstream of Jun-nuclear
kinase and p38. Apoptosis signaling kinase-1 overexpression activates nuclear factor κB to …

Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy

S Chen, CS Law, CL Grigsby, K Olsen, TT Hong… - Circulation, 2011 - Am Heart Assoc
Background—A variety of studies carried out using either human subjects or laboratory
animals suggest that vitamin D and its analogues possess important beneficial activity in the …

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

E Takimoto, HC Champion, M Li, D Belardi, S Ren… - Nature medicine, 2005 - nature.com
Sustained cardiac pressure overload induces hypertrophy and pathological remodeling,
frequently leading to heart failure. Genetically engineered hyperstimulation of guanosine …

The role of natriuretic peptides in cardioprotection

T Nishikimi, N Maeda, H Matsuoka - Cardiovascular research, 2006 - academic.oup.com
Atrial natriuretic peptide (ANP) and brain (B-type) natriuretic peptide (BNP) are circulating
hormones of cardiac origin that play an important role in the regulation of intravascular blood …