Animal models of inflammation for screening of anti-inflammatory drugs: implications for the discovery and development of phytopharmaceuticals

KR Patil, UB Mahajan, BS Unger, SN Goyal… - International journal of …, 2019 - mdpi.com
Inflammation is one of the common events in the majority of acute as well as chronic
debilitating diseases and represent a chief cause of morbidity in today's era of modern …

Emblica officinalis (Amla): A review for its phytochemistry, ethnomedicinal uses and medicinal potentials with respect to molecular mechanisms

BC Variya, AK Bakrania, SS Patel - Pharmacological research, 2016 - Elsevier
Medicinal plants, having great elementary and therapeutic importance, are the gift to
mankind to acquire healthy lifestyle. Emblica officinalis Gaertn. or Phyllanthus emblica …

Antibacterial activities of the extracts, fractions and isolated compounds from Canarium patentinervium Miq. against bacterial clinical isolates

R Mogana, A Adhikari, MN Tzar, R Ramliza… - … medicine and therapies, 2020 - Springer
Background Canarium patentinervium leaves are used by the local indigenous people of
Malaysia for wound healing. The current study is undertaken to screen the comprehensive …

Phytochemicals as anti-inflammatory agents in animal models of prevalent inflammatory diseases

SA Shin, BJ Joo, JS Lee, G Ryu, M Han, WY Kim… - Molecules, 2020 - mdpi.com
Phytochemicals are known to have anti-inflammatory effects in vitro and in vivo, such as in
inflammatory disease model systems. Inflammation is an essential immune response to …

Anti-inflammatory effects of compounds alpha-humulene and (−)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea

ES Fernandes, GF Passos, R Medeiros… - European journal of …, 2007 - Elsevier
This study evaluated the anti-inflammatory properties of two sesquiterpenes isolated from
Cordia verbenacea's essential oil, α-humulene and (−)-trans-caryophyllene. Our results …

Plant‐derived anti‐inflammatory compounds: Hopes and disappointments regarding the translation of preclinical knowledge into clinical progress

R Fürst, I Zündorf - Mediators of inflammation, 2014 - Wiley Online Library
Many diseases have been described to be associated with inflammatory processes. The
currently available anti‐inflammatory drug therapy is often not successful or causes …

Recent developments in anti‐inflammatory natural products

R Gautam, SM Jachak - Medicinal research reviews, 2009 - Wiley Online Library
Many of the inflammatory diseases are becoming common in aging society throughout the
world. The clinically used anti‐inflammatory drugs suffer from the disadvantage of side …

Molecular mechanism underlying anti-inflammatory and anti-allergic activities of phytochemicals: an update

Y Bellik, L Boukraâ, HA Alzahrani, BA Bakhotmah… - Molecules, 2012 - mdpi.com
The resort worldwide to edible medicinal plants for medical care has increased significantly
during the last few years. Currently, there is a renewed interest in the search for new …

Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid

MD Dos Santos, MC Almeida, NP Lopes… - Biological and …, 2006 - jstage.jst.go.jp
Phenolic compounds are numerous and ubiquitous in the plant kingdom, being particularly
present in health-promoting foods. Epidemiological evidences suggest that the consumption …

Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules

JB Calixto, MM Campos, MF Otuki… - Planta medica, 2004 - thieme-connect.com
It has been widely shown that many plant-derived compounds present significant anti-
inflammatory effects. For this reason, they represent potential molecules for the development …