Autosomal recessive (AR) gene defects are the leading genetic cause of intellectual
disability (ID) in countries with frequent parental consanguinity, which account for about …

Hemoglobinopathies are the most common single gene disorders (monogenic disorders) in
the world population. Due to specific position of Iran and the presence of multi-ethnic groups …

The clinical utility of genetic tests is determined by the outcomes following test use. Like
other measures of value, it is often contested. Stakeholders may have different views about …

An essential guide to this major contemporary issue, Consanguinity in Context is a uniquely
comprehensive account of intra-familial marriage. Detailed information on past and present …

Background β Thalassemia major is characterized by hemolytic anemia, ineffective
erythropoiesis and hemosiderosis. About 4% of the world population carries a Thalassemia …

Background: Iran is one of the countries located on “the thalassemia belt” with a significant
annual number of thalassemia new births. Given the importance of thalassemia prevention …

Abstract Background and Aims Cutaneous leishmaniasis (CL) is a severe parasitic disease
affecting people, mostly in underdeveloped nations. As a zoonotic infection yearly incidence …

β-Thalassemia (thal) is one of the most common autosomal recessive disorders in Iran.
There are more than two million carriers of β-thal and over 15,000 people affected with β …

Abstract α thalassemia (α-thal) is one of the most common hemoglobin (Hb) disorders in the
world. 1 α-globin genes are located on chromosome 16. The majority of α-thal mutations are …

Two hundred and fifty-five patients from Mazandaran Province, Iran, all presenting with
hypochromic and microcytic anemia, were selected for α-thalassemia (α-thal) mutation …