Free radicals are chemical species (atoms, molecules, or ions) containing one or more
unpaired electrons in their external orbitals and generally display a remarkable reactivity …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Exercise represents a major challenge to whole-body homeostasis provoking widespread
perturbations in numerous cells, tissues, and organs that are caused by or are a response to …

Introduction The intestinal microbiota comprises bacteria, fungi, archaea, protists, helminths
and viruses that symbiotically inhabit the digestive system. To date, research has provided …

Physical exercise represents a major challenge to whole-body homeostasis, provoking
acute and adaptative responses at the cellular and systemic levels. Different sources of …

Specificity is a core principle of exercise training to promote the desired adaptations for
maximising athletic performance. The principle of specificity of adaptation is underpinned by …

Mental fatigue reflects a change in psychobiological state, caused by prolonged periods of
demanding cognitive activity. It has been well documented that mental fatigue impairs …

The transcription factor EB (TFEB) is an essential component of lysosomal biogenesis and
autophagy for the adaptive response to food deprivation. To address the physiological …

Background Both athletes and recreational exercisers often perform relatively high volumes
of aerobic and strength training simultaneously. However, the compatibility of these two …

Page 1 Periodization Theory and Methodology of Training Sixth Edition Tudor O. Bompa, PhD
Carlo A. Buzzichelli Page 2 Library of Congress Cataloging-in-Publication Data Names …