Transcription factors play an indispensable role in maintaining cellular viability and finely
regulating complex internal metabolic networks. These crucial bioactive functions rely on …

Genetically encoded biosensors are crucial for enhancing our understanding of how
molecules regulate biological systems. Small molecule biosensors, in particular, help us …

The development of efficient, low-cost, and robust expression systems is important for the
mass production of proteins and natural products in large amounts using cell factories …

Inspired by natural evolution, directed evolution randomly mutates the gene of interest
through artificial evolution conditions with variants being screened for the required …

Enzyme engineering is a powerful tool for improving or altering the properties of biocatalysts
for industrial, research, and therapeutic applications. Fast and accurate screening of variant …

Transcription factor (TF)-based biosensors (TFBs) have received considerable attention in
various fields due to their capability of converting biosignals, such as molecule …

Nitrile hydratase (NHase) is a metalloenzyme that catalyzes the conversion of nitrile to
amide and is widely used in the biocatalysis of bulk chemicals such as acrylamide and …

S-Adenosylmethionine (SAM) is a crucial small-molecule metabolite widely used in food and
medicine. The development of high-throughput biosensors for SAM biosynthesis can …

Amides are an important type of synthetic intermediate used in the chemical, agrochemical,
pharmaceutical, and nutraceutical industries. The traditional chemical process of converting …

This study, with the goal of cultivating green and low-carbon talents, aims to enhance
students' practical skills by constructing an immersive practical teaching platform. This …