Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

Native mass spectrometry (nMS) has emerged as an important tool in studying the structure
and function of macromolecules and their complexes in the gas phase. In this review, we …

Mass spectrometry is a central technology in the life sciences, providing our most
comprehensive account of the molecular inventory of the cell. In parallel with developments …

Biological membranes formed of amphipathic lipid bilayers provide chemical barriers to
separate cells from their external environments and define subcellular compartments …

In biology, it can be argued that if the genome contains the script for a cell's life cycle, then
the proteome constitutes an ensemble cast of actors that brings these instructions to life …

Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

In recent years, there has been increasing interest in top-down mass spectrometry (TDMS)
approaches for protein analysis, driven both by technological advancements and efforts …

Mass spectrometry is well-established as one of the primary methods used to characterize
peptides and proteins. New advances in instrumentation and innovative analytical workflows …

Multidimensional multiple-stage tandem processing of ions is demonstrated successfully in
a novel segmented linear ion trap. The enhanced performance is enabled by incorporating …

Progress in structural biology research has led to a high demand for powerful and yet
complementary analytical tools for structural characterization of proteins and protein …