Bioavailability enhancement of poorly soluble raloxifene by designing inclusion complex with...

Enhancing the solubility and bioactivity of anticancer drug tamoxifen by water-soluble pillar [6] arene-based host–guest complexation

L Shangguan, Q Chen, B Shi, F Huang - Chemical Communications, 2017 - pubs.rsc.org

Enhancing the solubility and bioactivity of anticancer drug tamoxifen by water-soluble pillar[6]arene-based
host–guest complexation - Chemical Communications (RSC Publishing) DOI:10.1039/C7CC05305C …

被引用次数：50 相关文章所有 4 个版本

Oral bioavailability enhancement of raloxifene by developing microemulsion using D-optimal mixture design: optimization and in-vivo pharmacokinetic study

N Shah, A Seth, R Balaraman, G Sailor… - Drug Development …, 2018 - Taylor & Francis

The objective of this work was to utilize a potential of microemulsion for the improvement in
oral bioavailability of raloxifene hydrochloride, a BCS class-II drug with 2% bioavailability …

被引用次数：27 相关文章所有 3 个版本

[PDF] academia.edu

Solubility determination of raloxifene hydrochloride in ten pure solvents at various temperatures: Thermodynamics-based analysis and solute–solvent interactions

A Ahad, F Shakeel, OA Alfaifi, M Raish, A Ahmad… - International Journal of …, 2018 - Elsevier

The purpose of the present study was to determine the solubility of raloxifene hydrochloride
(RHCl) in ten solvents: water, ethanol, isopropyl alcohol (IPA), ethylene glycol (EG) …

被引用次数：25 相关文章所有 5 个版本

[PDF] researchgate.net

[PDF][PDF] Development of Risedronate Sodium-loaded Nanosponges by Experimental Design: Optimization and in vitro Characterization.

KD Pandya, NV Shah, DY Gohil, AK Seth… - Indian Journal of …, 2019 - researchgate.net

The present investigation focussed on the development of a novel strategy to enhance the
bioavailability of risedronate sodium, which has poor and erratic absorption. Nanosponges …

被引用次数：20 相关文章所有 2 个版本

[PDF] mui.ac.ir

Poly (methyl vinyl ether-co-maleic acid) for enhancement of solubility, oral bioavailability and anti-osteoporotic effects of raloxifene hydrochloride

J Varshosaz, M Minaiyan, L Dayyani - European Journal of Pharmaceutical …, 2018 - Elsevier

Raloxifene HCl (RH) has poor water solubility and due to its extensive first pass metabolism;
its bioavailability is only 2%. The purpose of the present study was to enhance the aqueous …

被引用次数：20 相关文章所有 4 个版本

Formulation and characterization of raloxifene nanostructured lipid carriers for permeability and uptake enhancement applications

A Sharma, J Streets, P Bhatt, P Patel… - ASSAY and Drug …, 2022 - liebertpub.com

Raloxifene (RLX), a biopharmaceutical classification system (BCS) class II drug, is a
selective estrogen receptor modulator (SERM) having an estrogenic effect on the bone and …

被引用次数：3 相关文章所有 5 个版本

[PDF] researchsquare.com

Study on protolytic equilibria and the effects of pH, cyclodextrins and polysorbate 80 on solubility of raloxifene hydrochloride

MR Popović-Nikolić, M Čakar, N Todorović, K Nikolić… - Chemical Papers, 2024 - Springer

The acid–base equilibria of raloxifene and the mutual influence of pH and solubility
enhancers on the solubility of raloxifene hydrochloride were studied. The apparent …