The success of regenerative medicine in various clinical applications depends on the
appropriate selection of the source of mesenchymal stem cells (MSCs). Indeed, the source …

The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

Cranial neural crest cells are an evolutionary innovation of vertebrates for craniofacial
development and function, yet the mechanisms that govern the cell fate decisions of …

Dental pulp regeneration is ideal for irreversible pulp or periapical lesions, and in situ stem
cell therapy is one of the most effective therapies for pulp regeneration. In this study, we …

The gastrointestinal tract is a multi-organ system crucial for efficient nutrient uptake and
barrier immunity. Advances in genomics and a surge in gastrointestinal diseases, has …

Dental pulp stem cells (DPSC) usually remain quiescent in the dental pulp tissue; however,
once the dental pulp tissue is injured, DPSCs potently proliferate and migrate into the injury …

Oral and craniofacial tissues are uniquely adapted for continuous and intricate functioning,
including breathing, feeding, and communication. To achieve these vital processes, this …

Periodontal tissue stem cells, which play a crucial role in maintaining the homeostasis of
periodontal tissues, are found in the periodontal ligament (PDL). These cells have long been …

Neural crest-derived mesenchymal stem cells (MSCs) are known to play an essential
function during tooth and skeletal development. PRX1+ cells constitute an important MSC …

Oral inflammatory diseases such as apical periodontitis are common bacterial infectious
diseases that may affect the periapical alveolar bone tissues. A protective process occurs …