[HTML][HTML] Adipose tissue immunomodulation: a novel therapeutic approach in cardiovascular and metabolic diseases

I AlZaim, SH Hammoud, H Al-Koussa… - Frontiers in …, 2020 - frontiersin.org
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …

Human perivascular adipose tissue dysfunction as a cause of vascular disease: focus on vascular tone and wall remodeling

G Ozen, A Daci, X Norel, G Topal - European journal of pharmacology, 2015 - Elsevier
Obesity is one of the major risk factors for the development of cardiovascular diseases. It is
characterized by excessive or abnormal accumulation of adipose tissue, including depots …

[HTML][HTML] Determinants of body weight regulation in humans

M Moehlecke, LH Canani, MRM Trindade… - … of endocrinology and …, 2016 - SciELO Brasil
Body weight is regulated by the ability of hypothalamic neurons to orchestrate behavioral,
endocrine and autonomic responses via afferent and efferent pathways to the brainstem and …

Adipose‐related microRNAs as modulators of the cardiovascular system: the role of epicardial adipose tissue

D Santos, E Carvalho - The Journal of Physiology, 2022 - Wiley Online Library
Adipose tissue expansion and subsequent metabolic dysfunction has been considered one
of the major risk factors for development of cardiometabolic disease. Epicardial adipose …

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

NMZ Bakkar, I AlZaim, AF El-Yazbi - Clinical Science, 2022 - portlandpress.com
Abstract Sodium-glucose transporter-2 inhibitors (SGLT-2i) and glucagon-like peptide 1
(GLP-1) receptor agonists are newer antidiabetic drug classes, which were recently shown …

[HTML][HTML] Unraveling the role of resistin, retinol-binding protein 4 and adiponectin produced by epicardial adipose tissue in cardiac structure and function: evidence of a …

GA Christou, CE Andriopoulou, A Liakopoulou… - Hormones, 2023 - Springer
Purpose Adipokines produced by adipose tissue have been found to be involved in the
pathophysiology of metabolic and cardiovascular diseases. We aimed to investigate the …

Interplay between epicardial adipose tissue, metabolic and cardiovascular diseases

O Bornachea, A Vea, V Llorente-Cortes - Clínica e Investigación en …, 2018 - Elsevier
Cardiovascular disease is the primary cause of death in obese and diabetic patients. In
these groups of patients, the alterations of epicardial adipose tissue (EAT) contribute to both …

[HTML][HTML] Role of resistin in cardiovascular diseases: Implications for prevention and treatment

M Rachwalik, M Hurkacz… - … in Clinical and …, 2021 - advances.umw.edu.pl
Cardiovascular diseases (CVDs) are associated with socioeconomic and, most importantly,
with clinical problems. Accordingly, the identification of early and specific biomarkers …

[HTML][HTML] Evaluation of the usefulness of determining the level of selected inflammatory biomarkers and resistin concentration in perivascular adipose tissue and …

M Rachwalik, M Matusiewicz, M Jasiński… - Lipids in Health and …, 2023 - Springer
Background The development of coronary artery disease (CAD) is related to the impaired
quantity and composition of inflammatory proteins found in plasma and tissue, such as …

Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches?

K Rietdorf, H MacQueen - British journal of pharmacology, 2017 - Wiley Online Library
Heart disease is a major cause of morbidity and mortality throughout the world. Some
cardiovascular conditions can be modulated by lifestyle factors such as increased exercise …