Molecular and cellular basis of genetically inherited skeletal muscle disorders
JJ Dowling, CC Weihl, MJ Spencer - Nature Reviews Molecular Cell …, 2021 - nature.com
Neuromuscular disorders comprise a diverse group of human inborn diseases that arise
from defects in the structure and/or function of the muscle tissue—encompassing the muscle …
from defects in the structure and/or function of the muscle tissue—encompassing the muscle …
Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin
In skeletal muscle, nebulin stabilizes and regulates the length of thin filaments, but the
underlying mechanism remains nebulous. In this work, we used cryo–electron tomography …
underlying mechanism remains nebulous. In this work, we used cryo–electron tomography …
The mechanisms of thin filament assembly and length regulation in muscles
The actin containing tropomyosin and troponin decorated thin filaments form one of the
crucial components of the contractile apparatus in muscles. The thin filaments are organized …
crucial components of the contractile apparatus in muscles. The thin filaments are organized …
Preclinical assessment on neuronal regeneration in the injury-related microenvironment of graphene-based scaffolds
As the application of graphene nanomaterials gets increasingly attractive in the field of
tissue engineering and regenerative medicine, the long-term evaluation is necessary and …
tissue engineering and regenerative medicine, the long-term evaluation is necessary and …
A nemaline myopathy–linked mutation inhibits the actin-regulatory functions of tropomodulin and leiomodin
LE Schultz, M Colpan, GE Smith Jr… - Proceedings of the …, 2023 - National Acad Sciences
Actin is a highly expressed protein in eukaryotic cells and is essential for numerous cellular
processes. In particular, efficient striated muscle contraction is dependent upon the precise …
processes. In particular, efficient striated muscle contraction is dependent upon the precise …
Transcriptome analysis reveals the molecular regulatory network of muscle development and meat quality in Sunit lamb supplemented with dietary probiotic
M Zhang, Y Guo, R Su, M Corazzin, R Hou, J Xie… - Meat Science, 2022 - Elsevier
Supplementing animal feed with probiotic additives can promote muscle production and
improve meat quality. The study aimed to explore the effects of dietary probiotics …
improve meat quality. The study aimed to explore the effects of dietary probiotics …
Postmortem Muscle Proteome Characteristics of Silver Carp (Hypophthalmichthys molitrix): Insights from Full-Length Transcriptome and Deep 4D Label-Free …
X Jiao, X Li, N Zhang, W Zhang, B Yan… - Journal of Agricultural …, 2024 - ACS Publications
The coverage of the protein database directly determines the results of shotgun proteomics.
In this study, PacBio single-molecule real-time sequencing technology was performed on …
In this study, PacBio single-molecule real-time sequencing technology was performed on …
Postnatal skeletal muscle myogenesis governed by signal transduction networks: MAPKs and PI3K–Akt control multiple steps
T Endo - Biochemical and Biophysical Research …, 2023 - Elsevier
Skeletal muscle myogenesis represents one of the most intensively and extensively
examined systems of cell differentiation, tissue formation, and regeneration. Muscle …
examined systems of cell differentiation, tissue formation, and regeneration. Muscle …
The role of leiomodin in actin dynamics: A new road or a secret gate
D Tolkatchev, CC Gregorio, AS Kostyukova - The FEBS journal, 2022 - Wiley Online Library
Leiomodin is an important emerging regulator of thin filaments. As novel molecular, cellular,
animal model, and human data accumulate, the mechanisms of its action become clearer …
animal model, and human data accumulate, the mechanisms of its action become clearer …
Whole-Exome Sequencing Identifies Homozygote Nonsense Variants in LMOD2 Gene Causing Infantile Dilated Cardiomyopathy
R Sono, TM Larrinaga, A Huang, F Makhlouf, X Kang… - Cells, 2023 - mdpi.com
As an essential component of the sarcomere, actin thin filament stems from the Z-disk extend
toward the middle of the sarcomere and overlaps with myosin thick filaments. Elongation of …
toward the middle of the sarcomere and overlaps with myosin thick filaments. Elongation of …