Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Mechanisms and regulation of endothelial VEGF receptor signalling

M Simons, E Gordon, L Claesson-Welsh - Nature reviews Molecular …, 2016 - nature.com
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …

Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) signaling in angiogenesis: a crucial target for anti-and pro-angiogenic therapies

M Shibuya - Genes & cancer, 2011 - journals.sagepub.com
The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown
to play major roles not only in physiological but also in most pathological angiogenesis …

Phosphoinositides: tiny lipids with giant impact on cell regulation

T Balla - Physiological reviews, 2013 - journals.physiology.org
Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Signal transduction by vascular endothelial growth factor receptors

S Koch, L Claesson-Welsh - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Vascular endothelial growth factors (VEGFs) are master regulators of vascular development
and of blood and lymphatic vessel function during health and disease in the adult. It is …

Signal transduction by vascular endothelial growth factor receptors

S Koch, S Tugues, X Li, L Gualandi… - Biochemical …, 2011 - portlandpress.com
VEGFs (vascular endothelial growth factors) control vascular development during
embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There …

VEGF receptor signalling? In control of vascular function

AK Olsson, A Dimberg, J Kreuger… - … reviews Molecular cell …, 2006 - nature.com
Vascular endothelial growth-factor receptors (VEGFRs) regulate the cardiovascular system.
VEGFR1 is required for the recruitment of haematopoietic precursors and migration of …

Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

RV Iozzo, RD Sanderson - Journal of cellular and molecular …, 2011 - Wiley Online Library
Introduction• Perlecan: a pro‐angiogenic proteoglycan• Endorepellin, a C‐terminal fragment
of perlecan with anti‐angiogenic activity• Syndecans in cancer biology• Glypicans and the …

Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition

K Holmes, OL Roberts, AM Thomas, MJ Cross - Cellular signalling, 2007 - Elsevier
Vascular endothelial growth factors (VEGFs) regulate vascular development, angiogenesis
and lymphangiogenesis by binding to a number of receptors. VEGFR-1 is required for the …

Cellular and molecular analyses of vascular tube and lumen formation in zebrafish

SW Jin, D Beis, T Mitchell, JN Chen, DYR Stainier - 2005 - journals.biologists.com
Tube and lumen formation are essential steps in forming a functional vasculature. Despite
their significance, our understanding of these processes remains limited, especially at the …