Human aquaporins: functional diversity and potential roles in infectious and non-infectious diseases

AK Azad, T Raihan, J Ahmed, A Hakim, TH Emon… - Frontiers in …, 2021 - frontiersin.org
Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …

Expression, distribution and role of aquaporin water channels in human and animal stomach and intestines

C Zhu, Z Chen, Z Jiang - International journal of molecular sciences, 2016 - mdpi.com
Stomach and intestines are involved in the secretion of gastrointestinal fluids and the
absorption of nutrients and fluids, which ensure normal gut functions. Aquaporin water …

Role of aquaporin 1 signalling in cancer development and progression

Y Tomita, H Dorward, AJ Yool, E Smith… - International journal of …, 2017 - mdpi.com
Cancer is a major health burden worldwide. Despite the advances in our understanding of
its pathogenesis and continued improvement in cancer management and outcomes, there …

Colonic fluid and electrolyte transport 2022: an update

AB Negussie, AC Dell, BA Davis, JP Geibel - Cells, 2022 - mdpi.com
Colonic epithelial cells are responsible for maintaining a delicate balance between luminal
secretion and the absorption of fluids and ions. This review aims to discuss and update the …

[HTML][HTML] Water transport proteins–aquaporins (AQPs) in cancer biology

S Dajani, A Saripalli, N Sharma-Walia - Oncotarget, 2018 - ncbi.nlm.nih.gov
As highly conserved ubiquitous proteins, aquaporins (AQPs) play an imperative role in the
development and progression of cancer. By trafficking water and other small molecules …

Aquaporin 3 facilitates chemoresistance in gastric cancer cells to cisplatin via autophagy

X Dong, Y Wang, Y Zhou, J Wen, S Wang… - Cell death discovery, 2016 - nature.com
Cisplatin (cDDP) remains one of the first-line chemotherapeutic agents for gastric cancer
(GC) treatment, and resistance to cDDP is the major limitation in its clinical application …

Aquaporins: a new target for traditional Chinese medicine in the treatment of digestive system diseases

Y Huang, S Yan, Z Su, L Xia, J Xie, F Zhang… - Frontiers in …, 2022 - frontiersin.org
Aquaporins (AQPs) are a family of transmembrane proteins expressed in various organ
systems. Many studies have shown that the abnormal expression of AQPs is associated with …

Aquaporin 3 facilitates tumor growth in pancreatic cancer by modulating mTOR signaling

X Huang, L Huang, M Shao - Biochemical and biophysical research …, 2017 - Elsevier
Aquaporins (AQP) have been demonstrated to be dysregulated in many human cancers and
is thought to be involved in pancreatic carcinogenesis and progression. However, the …

Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats

D Song, X Liu, Y Diao, Y Sun… - Molecular …, 2018 - spandidos-publications.com
Myocardial ischemia, hypoxia and reperfusion injury are induced by aortic occlusion,
cardiac arrest and resuscitation during cardiopulmonary bypass (CPB), which can severely …

[HTML][HTML] Nutrition strategies to control post-weaning diarrhea of piglets: from the perspective of feeds

Q Tang, T Lan, C Zhou, J Gao, L Wu, H Wei, W Li… - Animal Nutrition, 2024 - Elsevier
Post-weaning diarrhea (PWD) is a globally significant threat to the swine industry.
Historically, antibiotics as well as high doses of zinc oxide and copper sulfate have been …