Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities
Huntington disease (HD) is a neurodegenerative disease caused by CAG repeat expansion
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …
Huntington's disease: a clinical review
P McColgan, SJ Tabrizi - European journal of neurology, 2018 - Wiley Online Library
Huntington's disease (HD) is a fully penetrant neurodegenerative disease caused by a
dominantly inherited CAG trinucleotide repeat expansion in the huntingtin gene on …
dominantly inherited CAG trinucleotide repeat expansion in the huntingtin gene on …
Current and possible future therapeutic options for Huntington's disease
MW Ferguson, CJ Kennedy… - Journal of central …, 2022 - journals.sagepub.com
Huntington's disease (HD) is an autosomal neurodegenerative disease that is characterized
by an excessive number of CAG trinucleotide repeats within the huntingtin gene (HTT). HD …
by an excessive number of CAG trinucleotide repeats within the huntingtin gene (HTT). HD …
Huntington disease
Huntington disease is devastating to patients and their families—with autosomal dominant
inheritance, onset typically in the prime of adult life, progressive course, and a combination …
inheritance, onset typically in the prime of adult life, progressive course, and a combination …
Biomedical applications of copper ionophores
V Oliveri - Coordination Chemistry Reviews, 2020 - Elsevier
Copper dyshomeostasis is associated with a plethora of diseases, supporting the possibility
of applying copper ionophores to regenerate the metal homeostasis and treat copper …
of applying copper ionophores to regenerate the metal homeostasis and treat copper …
Clinical practice with anti-dementia drugs: a revised (third) consensus statement from the British Association for Psychopharmacology
The British Association for Psychopharmacology coordinated a meeting of experts to review
and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs. As …
and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs. As …
Metals and Parkinson's disease: mechanisms and biochemical processes
G Bjorklund, V Stejskal, MA Urbina… - Current Medicinal …, 2018 - ingentaconnect.com
Genetic background accounts for only 5 to 10% of the reported cases of Parkinson's disease
(PD), while the remaining cases are of unknown etiology. It is believed that environmental …
(PD), while the remaining cases are of unknown etiology. It is believed that environmental …
Therapeutic approaches to Huntington disease: from the bench to the clinic
The 25 years since the identification of the gene responsible for Huntington disease (HD)
have stood witness to profound discoveries about the nature of the disease and its …
have stood witness to profound discoveries about the nature of the disease and its …
Polyphenols as potential metal chelation compounds against Alzheimer's disease
J Lakey-Beitia, AM Burillo, G La Penna… - Journal of …, 2021 - content.iospress.com
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …