Antibiotic resistance: a rundown of a global crisis

B Aslam, W Wang, MI Arshad, M Khurshid… - Infection and drug …, 2018 - Taylor & Francis
The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of
antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial …

Origins and evolution of antibiotic resistance

J Davies, D Davies - Microbiology and molecular biology reviews, 2010 - Am Soc Microbiol
Antibiotics have always been considered one of the wonder discoveries of the 20th century.
This is true, but the real wonder is the rise of antibiotic resistance in hospitals, communities …

Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

NR Gandhi, P Nunn, K Dheda, HS Schaaf, M Zignol… - The Lancet, 2010 - thelancet.com
Although progress has been made to reduce global incidence of drug-susceptible
tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant …

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

JA Caminero, G Sotgiu, A Zumla… - The Lancet infectious …, 2010 - thelancet.com
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally
thought to have high mortality rates. However, many cases can be treated with the right …

Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB and XDR-TB: systematic review and meta-analysis

G Sotgiu, R Centis, L D'Ambrosio… - European …, 2012 - Eur Respiratory Soc
Linezolid is used off-label to treat multidrug-resistant tuberculosis (MDR-TB) in absence of
systematic evidence. We performed a systematic review and meta-analysis on efficacy …

Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis

V Skripconoka, M Danilovits, L Pehme… - European …, 2013 - Eur Respiratory Soc
Multidrug-resistant and extensively drug-resistant tuberculosis (TB) are associated with
worse treatment outcomes for patients, including higher mortality, than for drug-sensitive …

Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis

K Dheda, T Gumbo, NR Gandhi, M Murray… - The lancet Respiratory …, 2014 - thelancet.com
Extensively drug-resistant tuberculosis is a burgeoning global health crisis mainly affecting
economically active young adults, and has high mortality irrespective of HIV status. In some …

Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action

KA Sacksteder, M Protopopova, CE Barry… - Future …, 2012 - Future Medicine
Existing drugs have limited efficacy against the rising threat of drug-resistant TB, have
significant side effects, and must be given in combinations of four to six drugs for at least 6 …

Drug resistance beyond extensively drug-resistant tuberculosis: individual patient data meta-analysis

GB Migliori, G Sotgiu, NR Gandhi… - European …, 2013 - Eur Respiratory Soc
The broadest pattern of tuberculosis (TB) drug resistance for which a consensus definition
exists is extensively drug-resistant (XDR)-TB. It is not known if additional drug resistance …

[HTML][HTML] Tuberculosis control in prisons: current situation and research gaps

M Dara, CD Acosta, NVSV Melchers… - International Journal of …, 2015 - Elsevier
Background Tuberculosis (TB) in penitentiary services (prisons) is a major challenge to TB
control. This review article describes the challenges that prison systems encounter in TB …