The Mediterranean diet (MedDiet), abundant in minimally processed plant-based foods, rich
in monounsaturated fat from olive oil, but lower in saturated fat, meats, and dairy products …

The bioactive sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) are a
recent addition to the lipids accumulated in obesity and have emerged as important …

It has been established, worldwide, that non-communicable diseases such as obesity,
diabetes, metabolic syndrome, and cardiovascular events account for a high percentage of …

Aims To investigate whether metabolic signature composed of multiple plasma metabolites
can be used to characterize adherence and metabolic response to the Mediterranean diet …

Several studies indicated how dietary patterns that were obtained from nutritional cluster
analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a …

More than 50 years after the Seven Countries Study, a large number of epidemiological
studies have explored the relationship between the Mediterranean diet (MD) and health …

Aims Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease
(CVD) events, especially cardiovascular death. As phospholipids have also been linked with …

The Mediterranean diet is considered as the foremost dietary regimen and its adoption is
associated with the prevention of degenerative diseases and an extended longevity. The …

Cerebral ischemia is caused by perturbations in blood flow to the brain that trigger
sequential and complex metabolic and cellular pathologies. This leads to brain tissue …

Intestinal farnesoid X receptor (FXR) signaling is involved in the development of obesity,
fatty liver disease, and type 2 diabetes. However, the role of intestinal FXR in atherosclerosis …