Abstract Hyperbaric oxygen therapy (HBOT), a technique through which 100% oxygen is
provided at a pressure higher than 1 atm absolute (ATA), has become a well-established …

Aging is characterized by a progressive loss of tissue integrity and functionality due to
disrupted homeostasis. Molecular oxygen is pivotal to maintain tissue functions, and aerobic …

The current coronavirus disease 2019 (COVID-19) pandemic has become an
unprecedented challenge for the healthcare system worldwide, with an overwhelming …

Introduction SARS-CoV-2 affects part of the innate immune response and activates an
inflammatory cascade stimulating the release of cytokines and chemokines, particularly …

Sepsis is a major clinical challenge, with therapy limited to supportive interventions.
Therefore, the search for novel remedial approaches is of great importance. We addressed …

Hyperbaric oxygen therapy (HBOT) is frequently used after soft tissue injuries and in diabetic
patients with ulcerated wounds; however, its ability to increase oxidative stress casts doubts …

The disease burden from diabetic kidney disease is large and growing. Effective therapies
are lacking, despite an urgent need. Hyperbaric oxygen therapy (HBOT) activates Nrf2 and …

UV exposure often triggers photoaging of the skin. Pharmacological treatment suffers from
severe side effects as well as poor efficacy because of insufficient skin penetration …

Oxidative stress is involved in the development of diabetes. Nitric oxide (NO) contributes to
oxidative stress, affects the synthesis of glutathione (GSH) in tissues and also regulates …

Background Hyperbaric oxygen therapy (HBOT) involves patients breathing 100% oxygen in
a pressurized chamber, above 1 atmosphere. Many centers are now promoting the use of …