The use of computational fluid dynamics in the development of ventricular assist devices

KH Fraser, ME Taskin, BP Griffith, ZJ Wu - Medical engineering & physics, 2011 - Elsevier
Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …

[HTML][HTML] A brief review of bio-tribology in cardiovascular devices

D Xie, YX Leng, FJ Jing, N Huang - Biosurface and Biotribology, 2015 - Elsevier
Progress in the field of cardiovascular devices has significantly contributed to the rapid
advancements in cardiovascular disease therapy during the last fifty years. However, friction …

Numerical, hydraulic, and hemolytic evaluation of an intravascular axial flow blood pump to mechanically support Fontan patients

AL Throckmorton, JY Kapadia, SG Chopski… - Annals of biomedical …, 2011 - Springer
Currently available mechanical circulatory support systems are limited for adolescent and
adult patients with a Fontan physiology. To address this growing need, we are developing a …

Development of the centrifugal blood pump for a hybrid continuous flow pediatric total artificial heart: Model, make, measure

CS Fox, T Palazzolo, M Hirschhorn… - Frontiers in …, 2022 - frontiersin.org
Clinically-available blood pumps and total artificial hearts for pediatric patients continue to
lag well behind those developed for adults. We are developing a hybrid, continuous-flow …

Hybrid continuous‐flow total artificial heart

C Fox, S Chopski, N Murad, P Allaire… - Artificial …, 2018 - Wiley Online Library
Clinical studies using total artificial hearts (TAHs) have demonstrated that pediatric and adult
patients derive quality‐of‐life benefits from this form of therapy. Two clinically‐approved …

Validation of an axial flow blood pump: Computational fluid dynamics results using particle image velocimetry

B Su, LP Chua, X Wang - Artificial Organs, 2012 - Wiley Online Library
A magnetically suspended axial flow blood pump is studied experimentally in this article.
The pump casing enclosed a three‐blade straightener, a two‐blade impeller shrouded by a …

Design of Axial Blood Pumps for Patients With Dysfunctional F ontan Physiology: Computational Studies and Performance Testing

DH Kafagy, TW Dwyer, KL McKenna, JP Mulles… - Artificial …, 2015 - Wiley Online Library
Limited treatment options for patients having dysfunctional single ventricle physiology
motivate the necessity for alternative therapeutic options. To address this unmet need, we …

Suitability of different blood-analogous fluids in determining the pump characteristics of a ventricular assist device

F Knüppel, I Thomas, FH Wurm, B Torner - Fluids, 2023 - mdpi.com
Ventricular assist devices (VADs) are implantable turbomachines that save and improve the
lives of patients with severe heart failure. In the preclinical evaluation, a VAD design must be …

Pediatric circulatory support: current strategies and future directions. Biventricular and univentricular mechanical assistance

AL Throckmorton, SG Chopski - ASAIO Journal, 2008 - journals.lww.com
Mechanical circulatory support is gaining increased recognition as a viable treatment option
for pediatric patients who suffer from congenital or acquired heart disease. Historically, the …

Impellers, blood pumps, and methods of treating a subject

A Throckmorton, S Chopski - US Patent 10,350,341, 2019 - Google Patents
One embodiment of the invention provides a variable pitch impeller for a blood pump. The
variable pitch impeller includes: a flexible polymer defining a plurality of blades extending …